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母乳喂养持续时间和婴幼儿营养状况的研究。LAyDI 研究(PAPenRed)。

Breastfeeding duration and nutritional status of infants and toddlers in Spain. LAyDI study (PAPenRed).

机构信息

Servicio de Neonatología del Hospital Río Hortega, Valladolid, Spain.

Equipo coordinador PAPenRed, Instituto de investigación sanitaria del Principado de Asturias (ISPA), Oviedo, Asturias, Spain.

出版信息

An Pediatr (Engl Ed). 2024 Sep;101(3):172-182. doi: 10.1016/j.anpede.2024.08.003. Epub 2024 Sep 6.

Abstract

INTRODUCTION

Breastfeeding appears to protect the onset of obesity in infants. The aim is to know whether breastfeeding duration is associated with the risk of obesity in infants and toddlers aged 12 and 24 months.

MATERIAL AND METHODS

Prospective longitudinal study in a cohort of children born in Spain between April 2017 and March 2018 (LAyDI study) in the paediatric primary care system conducted in the framework of the PAPenRed research network. Analysis of breastfeeding duration (group 1: fewer than 6 months; group: more than 6 months) and its association with anthropometric variables.

RESULTS

A total of 1495 patients attended the 12 months preventive child health visit and 1073 patients the 24 months visit. We found a statistically significant association between breastfeeding duration and weight-for-age, BMI-for-age and weight-for-length/height at 12 and 24 months; breastfeeding duration of less than 6 months was significantly associated with overweight and obesity (based on BMI-for-age and weight-for-length/height) at ages 12 and 24 months. Maternal pre-pregnancy BMI acted as a modifier on the association between breastfeeding duration and overweight and obesity (based on BMI-for-age).

CONCLUSIONS

A breastfeeding duration of less than 6 months is associated with a higher percentage of overweight and obesity at ages 12 and 24 months, although maternal pre-pregnancy BMI modifies this relationship at 24 months.

摘要

引言

母乳喂养似乎可以预防婴儿肥胖的发生。本研究旨在探讨母乳喂养持续时间与 12 至 24 个月婴儿肥胖风险之间的关系。

材料与方法

这是一项在西班牙于 2017 年 4 月至 2018 年 3 月期间在儿科初级保健系统中开展的队列研究(LAyDI 研究),该研究隶属于 PAPenRed 研究网络。分析母乳喂养持续时间(第 1 组:少于 6 个月;第 2 组:多于 6 个月)及其与人体测量学变量的关系。

结果

共有 1495 名患者参加了 12 个月的预防儿童保健检查,1073 名患者参加了 24 个月的检查。我们发现,母乳喂养持续时间与 12 个月和 24 个月时的体重与年龄比、BMI 与年龄比和体重与身长/身高比之间存在统计学显著关联;母乳喂养持续时间少于 6 个月与 12 个月和 24 个月时超重和肥胖(基于 BMI 与年龄比和体重与身长/身高比)显著相关。母亲孕前 BMI 是母乳喂养持续时间与超重和肥胖(基于 BMI 与年龄比)之间关联的一个修饰因素。

结论

母乳喂养持续时间少于 6 个月与 12 个月和 24 个月时超重和肥胖的百分比增加相关,尽管母亲孕前 BMI 在 24 个月时会改变这种关系。

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