Pediatric Immunopathology and Allergology Unit, Policlinico Tor Vergata, University of Rome Tor Vergata, Rome, Italy.
Division of Pediatric Immunology and Rheumatology, Department of Public Health and Pediatrics, "Regina Margherita" Children Hospital, University of Turin, Turin, Italy.
Pediatr Allergy Immunol. 2024 Sep;35(9):e14236. doi: 10.1111/pai.14236.
Hypersensitivity reactions represent one of the most common causes of hesitancy for adherence to national vaccination programs. The majority of hypersensitivity reactions after vaccination are mild, and anaphylaxis is reported to be rare, although it remains challenging to estimate the frequency attributed to each single vaccine, either because of the lower number of administered doses of less common vaccines, or the administration of simultaneous vaccine in most of the vaccination programs. Although literature remains scattered, international consensus guides clinicians in identifying patients who might need the administration of vaccines in protected environments due to demonstrated hypersensitivity to vaccine components or adjuvants. Here we provide the current guidance on hypersensitivity reactions to vaccines and on vaccination of children with allergy disorders.
过敏反应是导致人们对接种国家疫苗计划犹豫不决的最常见原因之一。大多数疫苗接种后的过敏反应是轻度的，过敏反应虽然罕见，但仍难以估计归因于每种单一疫苗的频率，这要么是因为不太常见的疫苗接种剂量较少，要么是因为在大多数疫苗接种计划中同时接种疫苗。尽管文献仍然分散，但国际共识指导临床医生识别那些由于对疫苗成分或佐剂有明确的过敏反应而可能需要在保护环境中接种疫苗的患者。在这里，我们提供了关于疫苗过敏反应和过敏儿童疫苗接种的最新指南。
