Packaging Materials Department, National Research Centre, 33 El Bohouth St. (former El Tahrir St.), P.O. 12622, Dokki, Giza, Egypt.
Pre-treatment and Finishing of Cellulose-based Textiles Department, National Research Centre, 33 El Bohouth St. (former El Tahrir St.), P.O. 12622, Dokki, Giza, Egypt.
Int J Biol Macromol. 2024 Nov;279(Pt 3):135384. doi: 10.1016/j.ijbiomac.2024.135384. Epub 2024 Sep 6.
In this study, cotton fabric was treated with chitosan/alginate nanocapsules containing cinnamaldehyde (CINA) as a natural antibacterial and antioxidant. Cinnamaldehyde was encapsulated into chitosan/alginate complex coacervate (CINA@CH/ALG). FTIR, XRD, TEM, and SEM were utilized to investigate the formation of CINA@CH/ALG nanocapsules. The weight ratios of chitosan, alginate, and the volume fractions of cinnamaldehyde have a considerable impact on the particle size of the CINA@CH/ALG nanocapsules but no significant effect on the zeta potential. The lowest particle size was 549.8 nm at a weight ratio of 1/1 and 712.6 nm for CH/ALG nanocapsules containing cinnamaldehyde oil fractions of 0.025 mL. The maximum encapsulation (91.4 %) and loading percentage (12.0 %) were achieved with 0.025 mL of cinnamaldehyde. The highest cumulative release was 50.76 % with 0.025 mL of cinnamaldehyde over 300 min. The releasing mechanism of CINA from CINA(0.025)@CH/AG follows the bi-exponential model. The maximum radical scavenging activity was 72.91 % with 0.1 mL of CINA. CINA@CH/ALG nanocapsules were applied to cotton fabric. All tested pathogen strains were sensitive to CINA@CH/ALG, with a CINA volume fraction of 0.025 representing the minimum inhibitory concentration (MIC). Salmonella Typhimurium is the pathogen most prone to cinnamaldehyde with an inhibition zone of 18 mm. The coating of cotton fabric with CINA@CH/ALG has implanted antibacterial and antifungal properties.
在这项研究中，棉织物用壳聚糖/海藻酸钠纳米胶囊处理，其中含有肉桂醛（CINA）作为天然抗菌和抗氧化剂。肉桂醛被包封在壳聚糖/海藻酸钠复合凝聚物（CINA@CH/ALG）中。利用傅里叶变换红外光谱（FTIR）、X 射线衍射（XRD）、透射电子显微镜（TEM）和扫描电子显微镜（SEM）研究了 CINA@CH/ALG 纳米胶囊的形成。壳聚糖、海藻酸钠的重量比和肉桂醛的体积分数对 CINA@CH/ALG 纳米胶囊的粒径有很大影响，但对 Zeta 电位没有显著影响。在壳聚糖/海藻酸钠纳米胶囊中，当肉桂醛油分数为 0.025mL 时，重量比为 1/1 时的最小粒径为 549.8nm，712.6nm 时的粒径最小。当肉桂醛的浓度为 0.025mL 时，包封率（91.4%）和载药量（12.0%）最高。在 300min 内，肉桂醛的累积释放量最高为 50.76%。肉桂醛（0.025）@CH/AG 的释放机制符合双指数模型。肉桂醛的最大自由基清除活性为 72.91%，CINA 浓度为 0.1mL。CINA@CH/ALG 纳米胶囊应用于棉织物。所有测试的病原体菌株对 CINA@CH/ALG 敏感，肉桂醛体积分数为 0.025 时，最小抑菌浓度（MIC）。鼠伤寒沙门氏菌对肉桂醛最敏感，抑菌圈为 18mm。棉织物的 CINA@CH/ALG 涂层具有植入式抗菌和抗真菌性能。
