Giacometti Heloisa Helena Abil Russ, Coelho Laura Fernandes, Iankilevich Liana Grupenmacher, Valentin Livia Stocco Sanches, Ferreira Luciana Amizo, Balbino Marcos, Seixas Regina Cele Silveira
HR Oftalmologia e Oftalmo Curitiba, Curitiba, Brazil.
Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Front Psychol. 2024 Aug 22;15:1410890. doi: 10.3389/fpsyg.2024.1410890. eCollection 2024.
This study aimed to determine the prevalence of anxiety and depression among patients with glaucoma compared to the average Brazilian prevalence (9.8% of anxiety and 5.8% of depression, according to the World Health Organization) and its correlation with the severity of the disease.
This was a transversal, single-arm trial of patients from four glaucoma centers in São Paulo and Curitiba-Brazil. Patients comprised adults at least 18 years of age with glaucoma diagnosis under treatment for at least 6 months. All subjects of the study answered two questionnaires (PHQ-9 and GAD-7) to evaluate the presence of anxiety and depression, and the results were analyzed accordingly to clinical and demographic characteristics.
The protocol included a total of 210 patients. The average age was 61.6 ± 15.3 years, and the female gender was more common (68.86%). Primary open-angle glaucoma was the most common diagnosis (59.90%). The average IOP was 18.5 mmHg, and 1.5 anti-glaucoma drops were the mean treatment. The prevalence of depression and anxiety was 26.90 and 25.71%, respectively. Most patients with anxiety were classified as early glaucoma, while those with depression had severe glaucoma.
This study found that the prevalence of anxiety and depression among patients with glaucoma is higher than in the general population in our country.
本研究旨在确定青光眼患者中焦虑症和抑郁症的患病率，并与巴西平均患病率（根据世界卫生组织，焦虑症为9.8%，抑郁症为5.8%）进行比较，同时研究其与疾病严重程度的相关性。
这是一项对来自巴西圣保罗和库里蒂巴四个青光眼中心患者的横断面单臂试验。患者包括至少18岁、已确诊青光眼且接受治疗至少6个月的成年人。研究中的所有受试者均回答了两份问卷（PHQ-9和GAD-7）以评估焦虑和抑郁的存在情况，并根据临床和人口统计学特征对结果进行分析。
该方案共纳入210名患者。平均年龄为61.6±15.3岁，女性更为常见（68.86%）。原发性开角型青光眼是最常见的诊断（59.90%）。平均眼压为18.5 mmHg，平均使用1.5种抗青光眼药物治疗。抑郁症和焦虑症的患病率分别为26.90%和25.71%。大多数焦虑症患者被归类为早期青光眼，而抑郁症患者患有严重青光眼。
本研究发现，青光眼患者中焦虑症和抑郁症的患病率高于我国普通人群。
