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多发性结核性肠穿孔:一例报告

Multiple Tubercular Intestinal Perforations: A Case Report.

作者信息

Shetty Varun, Mathai Mathew John, Ali Iqbal M

机构信息

General Surgery, Dr. D. Y. Patil Medical College Hospital and Research Center, Dr. D. Y. Patil Vidyapeeth (Deemed to be University) Pimpri, Pune, IND.

出版信息

Cureus. 2024 Aug 7;16(8):e66352. doi: 10.7759/cureus.66352. eCollection 2024 Aug.

DOI:10.7759/cureus.66352
PMID:39246992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11378003/
Abstract

Intestinal tuberculosis (TB) is a frequently encountered pathology by surgeons all over India. There exists a vast body of knowledge about this disease; however, a detailed understanding of its presentation as well as surgical management is essential for every Indian surgeon, given its rampant nature. This report discusses the case of a 28-year-old female presenting with severe left upper abdominal pain, non-bilious vomiting, and fever, who was ultimately diagnosed with small bowel TB leading to perforations. Despite a history of pulmonary TB treated a year prior, the patient exhibited significant clinical and imaging findings, including pneumoperitoneum and peritonitis. Exploratory laparotomy revealed multiple tubercular perforations in the mid-jejunum and a stricture causing proximal jejunal dilatation. Surgical intervention involved resection of the affected segment and end-to-end anastomosis. Histopathological analysis confirmed TB as the cause. This case underscores the importance of considering TB in the differential diagnosis of small bowel perforations and highlights the critical role of timely surgical intervention and comprehensive management in improving patient outcomes.

摘要

肠结核在印度各地的外科医生中是一种常见的病症。关于这种疾病已有大量的知识;然而,鉴于其猖獗的性质,每位印度外科医生都必须详细了解其临床表现以及手术治疗方法。本报告讨论了一名28岁女性的病例,该患者出现严重左上腹疼痛、无胆汁性呕吐和发热,最终被诊断为小肠结核导致穿孔。尽管患者一年前有肺结核治疗史,但仍表现出显著的临床和影像学表现,包括气腹和腹膜炎。剖腹探查发现空肠中段有多个结核穿孔以及一处导致近端空肠扩张的狭窄。手术干预包括切除受影响的肠段并进行端端吻合。组织病理学分析证实结核为病因。该病例强调了在小肠穿孔的鉴别诊断中考虑结核的重要性,并突出了及时手术干预和综合管理在改善患者预后方面的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/1731af161e73/cureus-0016-00000066352-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/d525141044a0/cureus-0016-00000066352-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/2057d5f48257/cureus-0016-00000066352-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/877ef750f58c/cureus-0016-00000066352-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/1731af161e73/cureus-0016-00000066352-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/d525141044a0/cureus-0016-00000066352-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/2057d5f48257/cureus-0016-00000066352-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/877ef750f58c/cureus-0016-00000066352-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b8d/11378003/1731af161e73/cureus-0016-00000066352-i04.jpg

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本文引用的文献

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Tuberculosis treatment outcomes and associated factors among tuberculosis patients treated at healthcare facilities of Motta Town, Northwest Ethiopia: a five-year retrospective study.结核治疗结局及其相关因素分析:来自埃塞俄比亚西北莫塔镇医疗机构的五年回顾性研究。
Sci Rep. 2024 Apr 2;14(1):7695. doi: 10.1038/s41598-024-58080-0.
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Frequency, outcomes, and need for intervention in stricturing gastrointestinal tuberculosis: a systematic review and meta-analysis.狭窄性胃肠道结核的频率、结局和干预需求:系统评价和荟萃分析。
BMC Gastroenterol. 2023 Feb 23;23(1):46. doi: 10.1186/s12876-023-02682-x.
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Delayed Diagnosis of Intestinal Tuberculosis: A Case Report.
肠结核的延迟诊断:一例报告
Cureus. 2022 Oct 23;14(10):e30600. doi: 10.7759/cureus.30600. eCollection 2022 Oct.
4
Clinical profile and management of perforation peritonitis in Bharatpur hospital, Nepal: A prospective study.尼泊尔巴拉特普尔医院穿孔性腹膜炎的临床特征与管理:一项前瞻性研究。
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Ileal Perforation and Enteric Fever: Implications for Burden of Disease Estimation.回肠穿孔和肠热病:对疾病负担估计的影响。
J Infect Dis. 2021 Nov 23;224(Supple 5):S522-S528. doi: 10.1093/infdis/jiab258.
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Recent advances in the diagnosis of intestinal tuberculosis.肠结核的诊断进展。
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