• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

回肠直肠吻合术患者非甾体抗炎药使用相关的大量胃肠道出血

Massive Gastrointestinal Bleeding Related to NSAID Use in a Patient with Ileorectal Anastomosis.

作者信息

Nesiama Esere, Mirembe Letisha, Weber Kierra, Isaac Sruthy, Trammell Deborah, Obokhare Izi

机构信息

University of South Carolina School of Medicine/Prisma Health Department of Orthopaedic Surgery, Columbia, USA.

Texas Tech University Health Sciences Center Amarillo Department of Surgery, Amarillo, USA.

出版信息

Case Rep Surg. 2024 Aug 30;2024:4619458. doi: 10.1155/2024/4619458. eCollection 2024.

DOI:10.1155/2024/4619458
PMID:39247149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11379504/
Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to reduce pain and inflammation in over 30 million individuals daily. Gastrointestinal bleeding (GIB) associated with NSAID consumption has been well documented in gastric and duodenal bleeding; however, NSAID-associated GIB distal to the duodenum lacks extensive documentation. This report highlights small bowel occult bleeding related to NSAID use in a patient with a surgical history of robotic total colectomy with ileorectal anastomosis completed 1 year prior. In the case of bright red blood per rectum with associated NSAID use, we recommend NSAID cessation followed by an individualized treatment plan, such as upper/lower endoscopy and/or angioembolization.

摘要

非甾体抗炎药（NSAIDs）每天被超过3000万人用于减轻疼痛和炎症。与服用NSAIDs相关的胃肠道出血（GIB）在胃和十二指肠出血方面已有充分记录；然而，十二指肠远端与NSAIDs相关的GIB缺乏广泛的文献记载。本报告强调了1年前完成机器人全结肠切除术并进行回直肠吻合术的患者中与使用NSAIDs相关的小肠隐匿性出血。对于伴有NSAIDs使用且出现直肠鲜红色血便的情况，我们建议停用NSAIDs，随后制定个体化治疗方案，如上下消化道内镜检查和/或血管栓塞术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/8227c7d2433e/CRIS2024-4619458.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/2c9ac32f5bc6/CRIS2024-4619458.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/550aa311ebc9/CRIS2024-4619458.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/9474a09f58cf/CRIS2024-4619458.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/27c4372e2f16/CRIS2024-4619458.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/8227c7d2433e/CRIS2024-4619458.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/2c9ac32f5bc6/CRIS2024-4619458.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/550aa311ebc9/CRIS2024-4619458.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/9474a09f58cf/CRIS2024-4619458.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/27c4372e2f16/CRIS2024-4619458.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f3/11379504/8227c7d2433e/CRIS2024-4619458.005.jpg

相似文献

1
Massive Gastrointestinal Bleeding Related to NSAID Use in a Patient with Ileorectal Anastomosis.回肠直肠吻合术患者非甾体抗炎药使用相关的大量胃肠道出血
Case Rep Surg. 2024 Aug 30;2024:4619458. doi: 10.1155/2024/4619458. eCollection 2024.
2
Systematic reviews of the clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleeding.质子泵抑制剂治疗急性上消化道出血的临床疗效及成本效益的系统评价
Health Technol Assess. 2007 Dec;11(51):iii-iv, 1-164. doi: 10.3310/hta11510.
3
Acute upper gastrointestinal bleeding: comparison between recent users and nonusers of nonsteroidal anti-inflammatory drugs.急性上消化道出血：近期使用与未使用非甾体抗炎药者的比较
Endoscopy. 2003 Apr;35(4):327-32. doi: 10.1055/s-2003-38146.
4
Risk of Upper Gastrointestinal Injury and Events in Patients Treated With Cyclooxygenase (COX)-1/COX-2 Nonsteroidal Antiinflammatory Drugs (NSAIDs), COX-2 Selective NSAIDs, and Gastroprotective Cotherapy: An Appraisal of the Literature.环氧化酶（COX）-1/COX-2非甾体抗炎药（NSAIDs）、COX-2选择性NSAIDs及胃保护联合治疗患者的上消化道损伤风险与事件：文献评估
J Clin Rheumatol. 2004 Aug;10(4):178-89. doi: 10.1097/01.rhu.0000128851.12010.46.
5
Nonsteroidal anti-inflammatory drugs: add an anti-ulcer drug for patients at high risk only. Always limit the dose and duration of treatment with NSAIDs.非甾体抗炎药：仅对高危患者加用一种抗溃疡药物。始终限制非甾体抗炎药的治疗剂量和疗程。
Prescrire Int. 2011 Sep;20(119):216-9.
6
Striking prevalence of over-the-counter nonsteroidal anti-inflammatory drug use in patients with upper gastrointestinal hemorrhage.上消化道出血患者使用非处方非甾体抗炎药的惊人流行率。
Arch Intern Med. 1994 Jan 10;154(1):42-6.
7
[Recommendation for the prevention and treatment of non-steroidal anti-inflammatory drug-induced gastrointestinal ulcers and its complications].[非甾体抗炎药所致胃肠道溃疡及其并发症的防治建议]
Zhonghua Nei Ke Za Zhi. 2017 Jan 1;56(1):81-85. doi: 10.3760/cma.j.issn.0578-1426.2017.01.021.
8
Total abdominal colectomy and ileorectal anastomosis for inflammatory bowel disease.全腹结肠切除术及回肠直肠吻合术治疗炎性肠病
Dis Colon Rectum. 1997 Dec;40(12):1455-64. doi: 10.1007/BF02070712.
9
Non-steroidal anti-inflammatory drug related upper gastrointestinal bleeding: types of drug use and patient profiles in real clinical practice.非甾体抗炎药相关上消化道出血：真实临床实践中的用药类型及患者概况
Curr Med Res Opin. 2017 Oct;33(10):1815-1820. doi: 10.1080/03007995.2017.1338178. Epub 2017 Jul 5.
10
Are complications of subtotal colectomy with ileorectal anastomosis related to the original disease?回肠直肠吻合术式的次全结肠切除术并发症与原发病有关吗？
Am Surg. 2001 May;67(5):417-20.

本文引用的文献

1
The role of , and 1639 variants on the susceptibility of upper gastrointestinal bleeding: A full case-control study.1639 变体及其他因素在上消化道出血易感性中的作用：一项全病例对照研究。
J Pharm Pharm Sci. 2023 Jan 30;26:11136. doi: 10.3389/jpps.2023.11136. eCollection 2023.
2
Management of Patients With Acute Lower Gastrointestinal Bleeding: An Updated ACG Guideline.急性下消化道出血患者的管理：ACG 指南更新版。
Am J Gastroenterol. 2023 Feb 1;118(2):208-231. doi: 10.14309/ajg.0000000000002130. Epub 2022 Sep 21.
3
Pathophysiology of Inflammatory Bowel Disease: Innate Immune System.
炎症性肠病的病理生理学：固有免疫系统。
Int J Mol Sci. 2023 Jan 12;24(2):1526. doi: 10.3390/ijms24021526.
4
CT angiograms for lower GI bleeding: the experience of a large UK teaching hospital.CT 血管造影在胃肠道出血中的应用：英国一所大型教学医院的经验。
Ann R Coll Surg Engl. 2022 Feb;104(2):100-105. doi: 10.1308/rcsann.2021.0127. Epub 2021 Nov 3.
5
Factors predicting positive CT mesenteric angiography results in lower gastrointestinal haemorrhage prior to consideration of intra-arterial angio-embolisation.预测在考虑进行动脉内血管栓塞术之前，下消化道出血患者肠系膜 CT 血管造影阳性结果的因素。
J Med Imaging Radiat Oncol. 2021 Dec;65(7):841-845. doi: 10.1111/1754-9485.13176. Epub 2021 Mar 28.
6
Urgent Versus Standard Colonoscopy for Management of Acute Lower Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.紧急与标准结肠镜检查在急性下消化道出血治疗中的比较：一项随机对照试验的系统评价和荟萃分析。
J Clin Gastroenterol. 2020 Jul;54(6):493-502. doi: 10.1097/MCG.0000000000001329.
7
Diagnosis, Natural History and Treatment of Eosinophilic Enteritis: a Review.嗜酸性粒细胞性肠炎的诊断、自然史及治疗：综述
Curr Gastroenterol Rep. 2018 Jul 2;20(8):37. doi: 10.1007/s11894-018-0645-6.
8
Non-steroidal anti-inflammatory drug-induced enteropathy.非甾体抗炎药所致小肠病
Intest Res. 2017 Oct;15(4):446-455. doi: 10.5217/ir.2017.15.4.446. Epub 2017 Oct 23.
9
Clinical Pharmacology and Cardiovascular Safety of Naproxen.萘普生的临床药理学与心血管安全性
Am J Cardiovasc Drugs. 2017 Apr;17(2):97-107. doi: 10.1007/s40256-016-0200-5.
10
ACG Clinical Guideline: Management of Patients With Acute Lower Gastrointestinal Bleeding.美国胃肠病学会临床指南：急性下消化道出血患者的管理
Am J Gastroenterol. 2016 Apr;111(4):459-74. doi: 10.1038/ajg.2016.41. Epub 2016 Mar 1.