Radioresistance in brain tumors: Strategies for improved radiotherapy outcomes.
作者信息
Thiruvengadam Muthu
机构信息
Department of Applied Bioscience, College of Life and Environmental Science, Konkuk University, Seoul, 05029, Republic of Korea.
Center for Global Health Research, Saveetha Medical College & Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602 105, Tamil Nadu, India.
出版信息
Brain Spine. 2024 Aug 6;4:102912. doi: 10.1016/j.bas.2024.102912. eCollection 2024.
Abstract
摘要
相似文献
1
Radioresistance in brain tumors: Strategies for improved radiotherapy outcomes.脑肿瘤的放射抗性：改善放射治疗效果的策略。
Brain Spine. 2024 Aug 6;4:102912. doi: 10.1016/j.bas.2024.102912. eCollection 2024.
2
Targeting the AKT/cyclin D1 pathway to overcome intrinsic and acquired radioresistance of tumors for effective radiotherapy.靶向AKT/细胞周期蛋白D1通路以克服肿瘤的内在和获得性放射抗性从而实现有效的放射治疗。
Int J Radiat Biol. 2017 Apr;93(4):381-385. doi: 10.1080/09553002.2016.1257832. Epub 2016 Dec 2.
3
Targeting Epithelial-to-Mesenchymal Transition in Radioresistance: Crosslinked Mechanisms and Strategies.靶向放射抗性中的上皮-间质转化：交联机制与策略
Front Oncol. 2022 Feb 16;12:775238. doi: 10.3389/fonc.2022.775238. eCollection 2022.
4
Understanding the molecular mechanism responsible for developing therapeutic radiation-induced radioresistance of rectal cancer and improving the clinical outcomes of radiotherapy - A review.了解导致直肠癌治疗性辐射诱导放射抵抗的分子机制，并改善放射治疗的临床结果 - 综述。
Cancer Biol Ther. 2024 Dec 31;25(1):2317999. doi: 10.1080/15384047.2024.2317999. Epub 2024 Mar 6.
5
Repurposing Proton Beam Therapy through Novel Insights into Tumour Radioresistance.通过对肿瘤放射抵抗性的新认识来重新利用质子束疗法。
Clin Oncol (R Coll Radiol). 2021 Nov;33(11):e469-e481. doi: 10.1016/j.clon.2021.08.013. Epub 2021 Sep 9.
6
Nanoparticles (NPs)-Meditated LncRNA AFAP1-AS1 Silencing to Block Wnt/-Catenin Signaling Pathway for Synergistic Reversal of Radioresistance and Effective Cancer Radiotherapy.纳米颗粒介导的长链非编码RNA AFAP1-AS1沉默以阻断Wnt/β-连环蛋白信号通路，实现协同逆转放射抗性及有效的癌症放射治疗
Adv Sci (Weinh). 2020 Aug 5;7(18):2000915. doi: 10.1002/advs.202000915. eCollection 2020 Sep.
7
Radio-miRs: a comprehensive view of radioresistance-related microRNAs.放射 miRNAs：放射抵抗相关 microRNAs 的全面视图。
Genetics. 2024 Aug 7;227(4). doi: 10.1093/genetics/iyae097.
8
Difference in Acquired Radioresistance Induction Between Repeated Photon and Particle Irradiation.重复光子和粒子照射之间获得性放射抗性诱导的差异
Front Oncol. 2019 Nov 12;9:1213. doi: 10.3389/fonc.2019.01213. eCollection 2019.
9
The therapeutic targets of N6-methyladenosine (m6A) modifications on tumor radioresistance.N6-甲基腺苷（m6A）修饰对肿瘤放射抗性的治疗靶点。
Discov Oncol. 2023 Jul 31;14(1):141. doi: 10.1007/s12672-023-00759-3.
10
Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation.MycN 和 c-Myc 之间的相互作用调节了神经母细胞瘤在谷氨酰胺剥夺时的放射抵抗和癌症干细胞表型。
Theranostics. 2020 May 16;10(14):6411-6429. doi: 10.7150/thno.42602. eCollection 2020.
引用本文的文献
1
Beyond the Walls of Troy: A Scoping Review on Pharmacological Strategies to Enhance Drug Delivery Across the Blood-Brain Barrier and Blood-Tumor Barrier.超越特洛伊城墙：关于增强药物透过血脑屏障和血肿瘤屏障递送的药理学策略的范围综述
Int J Mol Sci. 2025 Jul 22;26(15):7050. doi: 10.3390/ijms26157050.
2
Emerging trends in cell-based therapies: contemporary advances and ethical considerations in translational neurosurgical oncology.基于细胞疗法的新趋势：转化神经外科肿瘤学的当代进展与伦理考量
J Neurooncol. 2025 Jul 22. doi: 10.1007/s11060-025-05170-2.
本文引用的文献
1
Radiotherapy, PARP Inhibition, and Immune-Checkpoint Blockade: A Triad to Overcome the Double-Edged Effects of Each Single Player.放射治疗、PARP抑制和免疫检查点阻断：克服单一治疗双刃剑效应的三联疗法。
Cancers (Basel). 2023 Feb 8;15(4):1093. doi: 10.3390/cancers15041093.
2
The efficacy of targeted therapy combined with radiotherapy and temozolomide-based chemotherapy in the treatment of glioma: A systemic review and meta-analysis of phase II/III randomized controlled trials.靶向治疗联合放疗及替莫唑胺化疗治疗胶质瘤的疗效：一项II/III期随机对照试验的系统评价和荟萃分析
Front Oncol. 2023 Jan 26;13:1082539. doi: 10.3389/fonc.2023.1082539. eCollection 2023.
3
Radiotherapeutic Strategies to Overcome Resistance of Breast Cancer Brain Metastases by Considering Immunogenic Aspects of Cancer Stem Cells.通过考虑癌症干细胞的免疫原性方面来克服乳腺癌脑转移耐药性的放射治疗策略
Cancers (Basel). 2022 Dec 29;15(1):211. doi: 10.3390/cancers15010211.
4
Signaling pathways in brain tumors and therapeutic interventions.脑肿瘤中的信号通路与治疗干预。
Signal Transduct Target Ther. 2023 Jan 4;8(1):8. doi: 10.1038/s41392-022-01260-z.
5
DNA Damage Repair in Brain Tumor Immunotherapy.脑肿瘤免疫治疗中的 DNA 损伤修复。
Front Immunol. 2022 Jan 13;12:829268. doi: 10.3389/fimmu.2021.829268. eCollection 2021.
6
Hypoxia-Induced Cancer Cell Responses Driving Radioresistance of Hypoxic Tumors: Approaches to Targeting and Radiosensitizing.缺氧诱导的癌细胞反应驱动缺氧肿瘤的放射抗性：靶向和放射增敏方法
Cancers (Basel). 2021 Mar 4;13(5):1102. doi: 10.3390/cancers13051102.
7
The Promise of Combining Radiation Therapy With Immunotherapy.放疗与免疫治疗联合的前景。
Int J Radiat Oncol Biol Phys. 2020 Sep 1;108(1):6-16. doi: 10.1016/j.ijrobp.2020.04.023. Epub 2020 Apr 23.
8
Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications.成人和儿童脑癌干细胞：细胞生物学及治疗意义
Neurotherapeutics. 2017 Apr;14(2):372-384. doi: 10.1007/s13311-017-0524-0.
9
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update.靶向癌症干细胞中的Notch、Hedgehog和Wnt信号通路：临床进展
Nat Rev Clin Oncol. 2015 Aug;12(8):445-64. doi: 10.1038/nrclinonc.2015.61. Epub 2015 Apr 7.
Zotero 插件