Ziff E B
Int Rev Cytol. 1985;93:327-58. doi: 10.1016/s0074-7696(08)61377-7.
Splicing provides viruses with great genetic versatility. It is still too early to say whether this versatility is derived from ingeneous mechanisms evolved by necessity by the viruses, or whether the viruses indeed mimic cellular mechanisms. In any event, it is unlikely that cells will provide a single genomic cluster of genes that utilize splicing in such diverse ways as adenovirus, or the other viruses discussed here. And we may speculate that when the full role of splicing in adenovirus gene expression program is known, its import will continue to be a source of amazement!
剪接赋予病毒极大的遗传多样性。现在判断这种多样性是源于病毒出于必要而演化出的巧妙机制，还是病毒确实模仿了细胞机制，还为时过早。无论如何，细胞不太可能提供一个单一的基因组基因簇，其利用剪接的方式像腺病毒或此处讨论的其他病毒那样多样。我们可以推测，当剪接在腺病毒基因表达程序中的全部作用为人所知时，它的重要性仍将令人惊叹不已！
