Department of Periodontology and Implant Dentistry, The Maurice and Gabriela Goldschleger, School of Dental Medicine, Faculty of Medical and Health Science, Tel Aviv University, Tel Aviv, Israel.
Clin Oral Investig. 2024 Sep 9;28(10):519. doi: 10.1007/s00784-024-05907-9.
Evaluate the inflammatory outcome of a two-piece novel titanium dental implant (test article) vs. a one- piece titanium dental implant (control article) inducing experimental peri-implantitis in a dog model.
MATERIALS & METHODS: A novel, two-piece pre-assembled implant with a 0.2-thickness sleeve in its coronal 4.2 mm part was developed (Test article). Ligature-induced experimental periimplantitis model was applied, followed by decontamination and bone grafting in seven dogs. Four groups were assessed according to decontamination and resurfacing protocol: E1 (Experimental 1): test article- sleeve removed, mechanical and chemical decontamination, new rough surface non-threaded sleeve was inserted; E2 (Experimental 2): test article- sleeve removed, mechanical and chemical decontamination, test article remained denuded presenting a turned non-threaded surface; C1 (Control 1): sleeve remained, mechanical and chemical decontamination in test article, original rough surface, non-threaded sleeve; C2 (Control 2): control article cleaning, mechanical and chemical decontamination of original rough surface, threaded implant. Buccolingual and mesiodistal sections were prepared for each site. Resin qualitative and semi-quantitative histopathologic inflammatory parameters were analyzed.
Group C1 showed statistically significant highest signs of residual long-term inflammation, followed by groups E1, and C2. Group E2 displayed the lowest local inflammation. Mesio/Distal aspects displayed increased long-term inflammatory infiltrate albeit not statistically significant.
Within the limits of the present study, it may be concluded that - (1) The decontamination procedure is more effective in a commercial one-piece vs. a two-piece dental implant. (2) Mechanical and chemical decontamination outcome is insufficient. Resurfacing improves the decontamination outcome. (3) Decontamination of the turned surface is superior to the rough surface.
When choosing the most appropriate dental implant for individuals with a high risk for peri-implant disease, a one-piece dental implant with a turned crestal surface is preferable. Once occurring, the control of peri-implant disease inflammation may be more successful. Decontamination is usually not enough. Resurfacing is highly recommended if possible.
评估新型两段式钛牙科种植体（试验用）与一段式钛牙科种植体（对照用）在犬模型中诱导实验性种植体周炎的炎症结果。
开发了一种新型的两段式预组装种植体，其冠部 4.2 毫米部分有一个 0.2 毫米厚的套管（试验用）。应用结扎诱导的实验性种植体周炎模型，随后在 7 只犬中进行了去污和骨移植。根据去污和再表面处理方案，将四个组评估为：E1（实验组 1）：套管去除，机械和化学去污，插入新的粗糙表面无螺纹套管；E2（实验组 2）：套管去除，机械和化学去污，裸露出经车削的无螺纹表面的试验用；C1（对照组 1）：套管保留，试验用中的机械和化学去污，原始粗糙表面，无螺纹套管；C2（对照组 2）：对照用清洁，机械和化学去污原始粗糙表面，螺纹种植体。每个部位制备颊舌和近远中截面。分析树脂定性和半定量组织病理学炎症参数。
C1 组显示出统计学上最高的残留长期炎症迹象，其次是 E1 组和 C2 组。E2 组显示出最低的局部炎症。近远中方面显示出长期炎症浸润增加，但无统计学意义。
在本研究的范围内，可以得出以下结论：（1）去污程序在商业一段式种植体中比两段式种植体更有效。（2）机械和化学去污效果不足。再表面处理可改善去污效果。（3）车削表面的去污效果优于粗糙表面。
在为患有种植体周病高风险的个体选择最合适的牙科种植体时，具有带冠部经车削表面的一段式牙科种植体是优选的。一旦发生种植体周疾病炎症，控制可能会更成功。去污通常是不够的。如果可能，强烈推荐再表面处理。
