Oral Implantology and Regenerative Dental Medicine, Department of Masticatory Function Rehabilitation, Graduate School of Medical Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Department of Oral Medicine, Periodontology, Oral Diagnosis, and Radiology, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
J Periodontol. 2016 Aug;87(8):953-61. doi: 10.1902/jop.2016.150615. Epub 2016 Mar 11.
Although oral rehabilitation with dental implants is a very promising and effective procedure, peri-implantitis is an emerging concern. Surgical and non-surgical methods have been applied to treat peri-implantitis together with various implant surface decontamination methods. However, there is no consensus concerning the most effective treatment for peri-implantitis. The aim of the present study is to evaluate the effects of erbium-doped:yttrium, aluminum, and garnet (Er:YAG) laser, photodynamic therapy (PDT), and titanium bur with and without citric acid on ligature-induced peri-implantitis around an anodized implant surface.
Thirty dental implants with anodized surface (3.3 × 10 mm) were installed in the mandibles of five beagle dogs. After 3 months, peri-implantitis was induced by applying cotton ligatures subgingivally. After ligature removal (baseline), the implants were divided into the following treatment groups: 1) Er:YAG laser, 2) PDT, 3) titanium bur alone, and 4) titanium bur with citric acid. Animals were sacrificed after 3 months, and clinical, radiologic, histologic, and histomorphometric evaluations were conducted for all treatment modalities. The data were analyzed using one-way analysis of variance and Tukey test. A value of P <0.05 was considered statistically significant.
The titanium bur with citric acid group exhibited statistically significantly greater improvement in vertical bone height than the Er:YAG laser group and significantly better bone-to-implant contact than the PDT group and the bur-alone group.
Within the limits of the study, the combination of mechanical and chemical treatment proved to be the most effective treatment for disinfection of the anodized implant surface.
尽管口腔种植体修复是一种非常有前途且有效的方法，但种植体周围炎仍是一个新兴的关注点。手术和非手术方法已被应用于治疗种植体周围炎，并结合各种种植体表面去污方法。然而，对于种植体周围炎的最有效治疗方法尚未达成共识。本研究旨在评估掺铒钇铝石榴石（Er:YAG）激光、光动力疗法（PDT）和钛钻（带或不带柠檬酸）对阳极氧化种植体表面结扎诱导的种植体周围炎的治疗效果。
将 30 个阳极氧化表面（3.3×10mm）的牙科种植体植入 5 只比格犬的下颌骨中。3 个月后，将种植体龈下结扎以诱导种植体周围炎。结扎去除（基线）后，将种植体分为以下治疗组：1）Er:YAG 激光，2）PDT，3）单独使用钛钻，和 4）钛钻联合柠檬酸。所有治疗方式完成 3 个月后处死动物，进行临床、放射学、组织学和组织形态计量学评估。采用单因素方差分析和 Tukey 检验进行数据分析。P<0.05 被认为具有统计学意义。
与 Er:YAG 激光组相比，柠檬酸钛钻组的垂直骨高度改善具有统计学意义，与 PDT 组和单独钛钻组相比，骨-种植体接触率改善具有统计学意义。
在本研究范围内，机械和化学联合治疗被证明是阳极氧化种植体表面消毒的最有效治疗方法。
