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REPRIEVE and CANTOS trials: lessons learned towards eliminating cardiovascular disease in human immunodeficiency virus by combined targeting of LDL and inflammation.

作者信息

Kirabo Annet

机构信息

Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.

Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA.

出版信息

Cardiovasc Res. 2025 Apr 22;121(2):219-221. doi: 10.1093/cvr/cvae152.

DOI:10.1093/cvr/cvae152
PMID:39250677
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12187055/
Abstract
摘要

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本文引用的文献

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Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV: Mechanistic Substudy of the REPRIEVE Randomized Clinical Trial.吡咯烷二硫代氨基甲酸盐对 HIV 患者冠心病及炎症生物标志物的影响：REPRIEVE 随机临床试验的机制亚研究。
JAMA Cardiol. 2024 Apr 1;9(4):323-334. doi: 10.1001/jamacardio.2023.5661.
2
Pitavastatin to Prevent Cardiovascular Disease in HIV Infection.匹伐他汀预防 HIV 感染患者的心血管疾病。
N Engl J Med. 2023 Aug 24;389(8):687-699. doi: 10.1056/NEJMoa2304146. Epub 2023 Jul 23.
3
DC ENaC-Dependent Inflammasome Activation Contributes to Salt-Sensitive Hypertension.DC ENaC 依赖性炎症小体激活导致盐敏感性高血压。
Circ Res. 2022 Aug 5;131(4):328-344. doi: 10.1161/CIRCRESAHA.122.320818. Epub 2022 Jul 12.
4
Colchicine in Patients with Chronic Coronary Disease.秋水仙碱治疗慢性冠心病
N Engl J Med. 2020 Nov 5;383(19):1838-1847. doi: 10.1056/NEJMoa2021372. Epub 2020 Aug 31.
5
Blood pressure, T cells, and mortality in people with HIV in Tanzania during the first 2 years of antiretroviral therapy.坦桑尼亚艾滋病毒感染者在抗逆转录病毒治疗的头 2 年中的血压、T 细胞与死亡率。
J Clin Hypertens (Greenwich). 2020 Sep;22(9):1554-1562. doi: 10.1111/jch.13975. Epub 2020 Aug 20.
6
Elevated Eosinophils as a Feature of Inflammation Associated With Hypertension in Virally Suppressed People Living With HIV.嗜酸性粒细胞升高是与 HIV 感染者病毒抑制相关的炎症伴发高血压的特征。
J Am Heart Assoc. 2020 Feb 18;9(4):e011450. doi: 10.1161/JAHA.118.011450. Epub 2020 Feb 17.
7
Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.心梗后小剂量秋水仙碱的疗效和安全性。
N Engl J Med. 2019 Dec 26;381(26):2497-2505. doi: 10.1056/NEJMoa1912388. Epub 2019 Nov 16.
8
IL-1β Inhibition Reduces Atherosclerotic Inflammation in HIV Infection.白细胞介素-1β抑制可减轻HIV感染中的动脉粥样硬化炎症。
J Am Coll Cardiol. 2018 Dec 4;72(22):2809-2811. doi: 10.1016/j.jacc.2018.09.038.
9
Low-Dose Methotrexate for the Prevention of Atherosclerotic Events.低剂量甲氨蝶呤预防动脉粥样硬化事件。
N Engl J Med. 2019 Feb 21;380(8):752-762. doi: 10.1056/NEJMoa1809798. Epub 2018 Nov 10.
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Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis.全球艾滋病毒感染者的动脉粥样硬化性心血管疾病负担：系统评价和荟萃分析。
Circulation. 2018 Sep 11;138(11):1100-1112. doi: 10.1161/CIRCULATIONAHA.117.033369.