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通过超高效液相色谱-四极杆飞行时间质谱（UPLC-Q-TOF-MS）从……中发现强效抗耐甲氧西林金黄色葡萄球菌（MRSA）成分，并通过深入的转录组学、……和……研究靶向青霉素结合蛋白2a（PBP2a）蛋白。 （注：原文中部分内容缺失，翻译可能不完全准确）

Discovery of potent anti-MRSA components from through UPLC-Q-TOF-MS and targeting PBP2a protein through in-depth transcriptomic, , and studies.

作者信息

Wu Jiajia, Hassan Syed Shams Ul, Zhang Xue, Li Tao, Rehman Abdur, Yan Shikai, Jin Huizi

机构信息

Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.

Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China.

出版信息

J Pharm Anal. 2024 Aug;14(8):100938. doi: 10.1016/j.jpha.2024.01.006. Epub 2024 Jan 23.

DOI:10.1016/j.jpha.2024.01.006
PMID:39253294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11381741/
Abstract

Image 1.

摘要

图1。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/11381741/9b3e261212a5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/11381741/a004e22b5c1f/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/11381741/9b3e261212a5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/11381741/a004e22b5c1f/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e6e/11381741/9b3e261212a5/gr1.jpg

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Comparative transcriptomic study of Escherichia coli O157:H7 in response to ohmic heating and conventional heating.大肠杆菌 O157:H7 对欧姆加热和传统加热响应的比较转录组学研究。
Food Res Int. 2021 Feb;140:109989. doi: 10.1016/j.foodres.2020.109989. Epub 2020 Dec 24.
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Transcriptome analysis of methicillin-resistant Staphylococcus aureus in response to stigmasterol and lupeol.
甾醇和羽扇豆醇对耐甲氧西林金黄色葡萄球菌转录组的影响分析。
J Glob Antimicrob Resist. 2017 Mar;8:48-54. doi: 10.1016/j.jgar.2016.10.006. Epub 2016 Dec 9.
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2,4,5-Trimethoxyldalbergiquinol promotes osteoblastic differentiation and mineralization via the BMP and Wnt/β-catenin pathway.2,4,5-三甲氧基黄檀醌通过骨形态发生蛋白（BMP）和Wnt/β-连环蛋白途径促进成骨细胞分化和矿化。
Cell Death Dis. 2015 Jul 16;6(7):e1819. doi: 10.1038/cddis.2015.185.