静脉注射氨茶碱对健康男性递增运动能力的影响。

Effect of intravenous aminophylline upon the incremental exercise performance of healthy men.

作者信息

Elliott C G, Nietrzeba R M, Adams T D, Crapo R O, Jensen R L, Yanowitz F G

出版信息

Respiration. 1985;47(4):260-6. doi: 10.1159/000194781.

DOI:10.1159/000194781

Abstract

Aminophylline increases the contractile force of fatiguing muscles. The effects of aminophylline upon maximal exercise performance are not defined. 6 healthy men performed incremental bicycle ergometry before and after receiving intravenous aminophylline (6 mg/kg). Maximal oxygen uptake, maximum work rate, and maximum minute ventilation were unchanged following aminophylline. Heart rate measured at rest and at 50-watt increments of work rate was significantly increased following aminophylline (p less than 0.03). The heart rate response to incremental exercise (delta HR/delta VO2) was unchanged by aminophylline. We conclude that aminophylline does not increase maximal exercise performance of healthy men.

摘要

氨茶碱可增强疲劳肌肉的收缩力。氨茶碱对最大运动能力的影响尚不明确。6名健康男性在静脉注射氨茶碱（6毫克/千克）前后进行了递增式自行车测力计测试。注射氨茶碱后，最大摄氧量、最大工作率和最大每分通气量均未改变。静息时以及工作率以50瓦递增时测得的心率在注射氨茶碱后显著升高（p<0.03）。氨茶碱未改变对递增运动的心率反应（心率变化/摄氧量变化）。我们得出结论，氨茶碱不会提高健康男性的最大运动能力。