Erhardt W, Köstlin R, Seiler R, Tonzer G, Tielebier-Langenscheidt B, Limmer R, Pfeiffer U, Blümel G
Tierarztl Prax Suppl. 1985;1:45-9.
General anesthesia causes a marked hypoxia in ruminants. We compared this phenomenon with anaesthesia related changes in the dog. Under alfentanil/etomidat anaesthesia some variables of the pulmonary circulation (TPR, PAP, PCWP) as well as arterial and venous blood gases and saturation (HbO2, pO2, ph) in dogs, sheep and calves were measured and calculated. The calculated pulmonary shunt fraction was compared between the three species. In ruminants there was an increase of total pulmonary resistance being associated with elevated PAP and decreased PCWP. The pulmonary shunt fraction was increased significantly and markedly during the surgical tolerance period, too. These parameters were not significantly changed in the dog. Ruminants seem to take an exceptional position concerning the anaesthesia related alterations of the pulmonary ventilation/perfusion system.
全身麻醉会导致反刍动物出现明显的低氧血症。我们将这种现象与狗在麻醉相关变化方面进行了比较。在阿芬太尼/依托咪酯麻醉下,测量并计算了狗、绵羊和小牛的一些肺循环变量(总外周阻力、肺动脉压、肺毛细血管楔压)以及动脉和静脉血气及饱和度(血红蛋白氧饱和度、氧分压、酸碱度)。比较了这三个物种之间计算得出的肺分流分数。在反刍动物中,总肺阻力增加,同时肺动脉压升高,肺毛细血管楔压降低。在手术耐受期,肺分流分数也显著且明显增加。这些参数在狗身上没有明显变化。在与麻醉相关的肺通气/灌注系统改变方面,反刍动物似乎处于特殊地位。