Yastrebov Konstantin, Brunel Laurencie M, Schnitzler Fiona C, Partel Lisa M, Paterson Hugh S, Bannon Paul G
Sydney Imaging Core Research Facility, The University of Sydney, Camperdown, 2006, Australia.
University of New South Wales, Randwick, Sydney, Australia.
J Cardiovasc Transl Res. 2025 Feb;18(1):70-78. doi: 10.1007/s12265-024-10555-1. Epub 2024 Sep 10.
The Impella CP is a percutaneously inserted temporary left ventricular assist device used in clinical practice and in translational research into cardiogenic shock, perioperative cardiac surgery, acute cardiac failure and mechanical circulatory support. Fluoroscopic guidance is usually used for insertion of an Impella, thus limiting insertion to within catheterization laboratories. Transthoracic, transoesophageal and intracardiac echocardiography have been reported to guide Impella CP implantation with identified specific limitations stemming from the surgical, anatomical and equipment factors. We conducted translational prospective descriptive feasibility investigation as a part of two other hemodynamic Impella studies. It showed the successful application of epicardial echocardiographic scanning for implantation of Impella CP devices in ovine models, from which details of the technique and identified pitfalls are described with practical solutions for future investigators and clinicians. Many described findings are relevant to any other echocardiographic techniques when adequate imaging of the Impella and relevant anatomical structures is achievable.
Impella CP是一种经皮插入的临时左心室辅助装置，用于临床实践以及心源性休克、围手术期心脏手术、急性心力衰竭和机械循环支持的转化研究。通常使用荧光透视引导来插入Impella，因此限制了其只能在导管实验室中进行插入操作。据报道，经胸、经食管和心内超声心动图可用于引导Impella CP植入，但由于手术、解剖和设备因素存在特定局限性。作为另外两项血流动力学Impella研究的一部分，我们进行了转化性前瞻性描述性可行性研究。该研究表明，心外膜超声心动图扫描在绵羊模型中成功用于植入Impella CP装置，并为未来的研究人员和临床医生描述了该技术的细节、识别出的陷阱以及实际解决方案。当能够对Impella和相关解剖结构进行充分成像时，许多所描述的发现与任何其他超声心动图技术都相关。
