[Modification of an immunoradiometric analysis method and the coagglutination reaction in the diagnosis of meningitis].

The coagglutination test and the radio-immunoassay (RIA) in the authors' modification have been used for the rapid diagnosis of meningococcal meningitis. This modification of RIA has been found to be highly sensitive with respect to soluble microbial antigens. In the study of liquors from patients with acute meningitides of different etiology RIA has been shown to have a higher efficiency in comparison with the coagglutination test. The data thus obtained indicate good prospects for the use of RIA in experimental and diagnostic investigations.