Demina A A, Il'ina T V
Zh Mikrobiol Epidemiol Immunobiol. 1985 Nov(11):3-6.
The results of the evaluation of the diagnostic latex preparations Bactigen, manufactured by Wampole Laboratories (USA) and intended for the detection of meningococcal antigens, serogropus A, B, C, Y, pneumococcal polyantigens and type b Haemophilus influenzae antigens in the spinal fluid and blood of patients with meningococcal infection and purulent bacterial meningitides, are presented. The pathological material was studied by traditional methods and by the latex agglutination (LAG) test. 522 LAG tests were made, including 414 tests for meningococcal infection, 60 tests for pneumococcal infection and 48 tests for type b H. influenzae. The results of this study revealed that the latex preparations were highly specific with respect to type b H. influenzae antigens and meningococcal antigens (false positive reactions constituted 0.96%). The simplicity of the test and the rapid techniques making it possible to obtain results within 30-40 minutes indicate good prospects of using the LAG test in laboratory practice.
本文介绍了由美国万波实验室生产的诊断用乳胶制剂Bactigen的评估结果，该制剂用于检测脑膜炎球菌感染及化脓性细菌性脑膜炎患者脑脊液和血液中的A、B、C、Y群脑膜炎球菌抗原、肺炎球菌多抗原和b型流感嗜血杆菌抗原。采用传统方法和乳胶凝集（LAG）试验对病理材料进行了研究。共进行了522次LAG试验，其中414次针对脑膜炎球菌感染，60次针对肺炎球菌感染，48次针对b型流感嗜血杆菌。本研究结果表明，乳胶制剂对b型流感嗜血杆菌抗原和脑膜炎球菌抗原具有高度特异性（假阳性反应占0.96%）。该试验操作简单，技术快速，可在30 - 40分钟内获得结果，表明LAG试验在实验室实践中有良好的应用前景。
