Ganesh Sandra, Lusobya Rebecca Claire, Uduman Mohammed Sithiq, Rajan Reshma, Rajendran Nisha, Sanjeev Kripa, Narendran Kalpana
Department of Pediatric Ophthalmology and Strabismus, Myopia Clinic, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India.
Department of Paediatric Ophthalmology and Strabismus, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India.
Indian J Ophthalmol. 2025 Feb 1;73(2):292-296. doi: 10.4103/IJO.IJO_546_24. Epub 2024 Sep 10.
This study aims to profile the ocular biometric parameters in a large group of children of South-Indian ethnicity who visited our outpatient children's department and were diagnosed with myopia.
Children <15 years old diagnosed with myopia (Jan 2022-Oct 2023) and who had ocular biometry readings recorded were included. Their demographics, axial length (AL), anterior chamber depth (ACD), spherical equivalent (SE), corneal radius of curvature (CR), and AL/CR ratio were analyzed.
The study included 3728 myopic children; the mean age was 11.85 (4-15) years, and 52.8% were girls. Mean SE was -3.98 D. The mean (SD) AL, ACD, CR, and AL/CR ratio were 24.64 (1.32), 3.73 (0.40), 7.61 (0.27), and 3.24 (0.16), respectively. Female gender was associated with shorter AL, ACD, CR, and AL/CR ratios ( P < 0.001) across all age groups. There was a significant increase in ACD with age in both sexes ( P < 0.001). A 1-unit (mm) increase in AL was associated with an SE increase of -1.65 D (CL: -1.70 to -1.60). AL/CR ratio could explain 71% of the total variance in SE ( P < 0.001). SE showed a mild correlation with age (rho = 0.14, P < 0.001) and ACD (rho = -0.03, P = 0.041) and a stronger correlation with AL (rho = -0.68, P < 0.001) and AL/CR (rho = -0.83, P < 0.001).
In this hospital-based study, AL and AL/CR ratios strongly correlate with SE, and the AL/CR better explains the total variance in SE than AL alone in children with myopia.
本研究旨在分析一大组前来我院儿科门诊就诊且被诊断为近视的南印度裔儿童的眼部生物测量参数。
纳入2022年1月至2023年10月期间诊断为近视且有眼部生物测量数据记录的15岁以下儿童。分析他们的人口统计学特征、眼轴长度（AL）、前房深度（ACD）、等效球镜度（SE）、角膜曲率半径（CR）以及AL/CR比值。
该研究纳入了3728名近视儿童；平均年龄为11.85（4 - 15）岁，52.8%为女孩。平均SE为 -3.98 D。平均（标准差）AL、ACD、CR以及AL/CR比值分别为24.64（1.32）、3.73（0.40）、7.61（0.27）和3.24（0.16）。在所有年龄组中，女性的AL、ACD、CR以及AL/CR比值均较低（P < 0.001）。男女两性的ACD均随年龄显著增加（P < 0.001）。AL每增加1个单位（mm），SE增加 -1.65 D（可信区间：-1.70至 -1.60）。AL/CR比值可解释SE总方差的71%（P < 0.001）。SE与年龄呈轻度相关（rho = 0.14，P < 0.001），与ACD呈轻度相关（rho = -0.03，P = 0.041），与AL呈较强相关（rho = -0.68，P < 0.001），与AL/CR呈更强相关（rho = -0.83，P < 0.001）。
在这项基于医院的研究中，近视儿童的AL和AL/CR比值与SE密切相关，且与单独的AL相比，AL/CR能更好地解释SE的总方差。
