Li Xin-Rong, Cheng Wen-Bo, Hu Lu-Mei, Zhang Hai-Nan, Peng Xing-Xing, Yi Xiang-Long
Department of Ophthalmology, Minda Hospital of Hubei Minzu University, Enshi 445000, Hubei Province, China.
Hubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases, Minda Hospital of Hubei Minzu University, Enshi 445000, Hubei Province, China.
Int J Ophthalmol. 2025 Jun 18;18(6):1105-1112. doi: 10.18240/ijo.2025.06.18. eCollection 2025.
To describe ocular biometric parameters among Han and Uyghur myopic adults in Xinjiang, China.
A cross-sectional study was conducted. The different ocular biometric parameters collected using Pentacam were analyzed, including corneal curvature, corneal astigmatism (CA), horizontal corneal diameter (white-to-white, WTW), corneal volume (CV), pupil diameter (PD), anterior chamber angle (ACA), anterior chamber depth (ACD), anterior chamber volume (ACV) and axial length (AL).
In total, 2932 participants were included in the final analysis, comprising 2310 Han and 622 Uyghur adults. Adults in the high myopia (HM) group had steeper K2, larger CA, smaller WTW and longer AL in both the Uyghur and Han adults (all <0.05). The moderate myopia (MM) and HM group had deeper ACV, ACD and wider ACA than the low myopia (all <0.05) in Han adults, however there were no differences in anterior chamber indices with Uyghur adults. In the Uyghur adults, we noticed that CV, WTW, and ACD were smaller, ACA was narrower, PD was larger, and AL was shorter (all <0.05). We also noticed sex differences: males had flatter corneas, deeper ACD and ACV, and larger WTW than females (all <0.05). In the correlation analysis, WTW was positively correlated with ACD and ACV but negatively correlated with K1, K2 and CV (all <0.05). Narrower ACA was associated with larger PD (U=-0.25, H=-0.16, all <0.01).
The Han population have different biometric parameters in eyes with HM compared to the Uyghur population, and the Uyghur population may anatomically more susceptible to primary angle closure glaucoma than the Han population.
描述中国新疆汉族和维吾尔族近视成年人的眼部生物测量参数。
进行一项横断面研究。分析使用Pentacam收集的不同眼部生物测量参数，包括角膜曲率、角膜散光（CA）、水平角膜直径（白对白，WTW）、角膜体积（CV）、瞳孔直径（PD）、前房角（ACA）、前房深度（ACD）、前房容积（ACV）和眼轴长度（AL）。
最终分析共纳入2932名参与者，包括2310名汉族和622名维吾尔族成年人。维吾尔族和汉族成年人中，高度近视（HM）组的成年人K2更陡峭、CA更大、WTW更小且AL更长（均P<0.05）。汉族成年人中，中度近视（MM）和HM组的ACV、ACD比低度近视组更深，ACA更宽（均P<0.05），然而维吾尔族成年人的前房指数无差异。在维吾尔族成年人中，我们注意到CV、WTW和ACD更小，ACA更窄，PD更大，AL更短（均P<0.05）。我们还注意到性别差异：男性角膜比女性更平坦，ACD和ACV更深，WTW更大（均P<0.05）。在相关性分析中，WTW与ACD和ACV呈正相关，但与K1、K2和CV呈负相关（均P<0.05）。更窄的ACA与更大的PD相关（U=-0.25，H=-0.16，均P<0.01）。
与维吾尔族人群相比，汉族人群中高度近视眼睛的生物测量参数不同，维吾尔族人群在解剖学上可能比汉族人群更容易患原发性闭角型青光眼。
