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帕金森病患者的运动锻炼:最新进展与未来考量

Exercise for People with Parkinson's Disease: Updates and Future Considerations.

作者信息

McGinley Jennifer L, Nakayama Yasuhide

机构信息

Physiotherapy Department, Melbourne School of Health Sciences, The University of Melbourne, Australia.

Department of Rehabilitation Medicine, The Jikei University School of Medicine, Japan.

出版信息

Phys Ther Res. 2024;27(2):67-75. doi: 10.1298/ptr.R0030. Epub 2024 Jul 19.

Abstract

Parkinson's disease (PD) is now the world's fastest-growing neurological disorder with rapidly rising prevalence and increasing demand for effective health services. Recent research has focused on the importance of early diagnosis and proactive management of physical function. Accumulating evidence indicates that reduced physical activity levels and mild pre-clinical disability are present in many people prior to a clinical diagnosis, perhaps developing over years. Early referral to a physiotherapist at the time of diagnosis is now recommended in global guidelines. Multiple forms of exercise have been found to have benefits in early and mid-stage disease across a range of motor and non-motor symptoms. Evidence from longitudinal studies confirms that disability is delayed when regular exercise is sustained over long periods. Exercise is now recognized as an essential component of treatment, in combination with medical therapies. Contemporary physiotherapy interventions now combine health behavior change techniques with physical exercise to promote the development of long-term exercise adherence. Advances in technology and digital health have progressed quickly and now offer opportunities for remote assessment and monitoring, remote exercise supervision, and support adherence through feedback and motivational strategies. Recent biomedical discoveries forecast improved earlier and more accurate diagnosis of PD, allowing opportunities for earlier interventions. Current research in progress will provide important insights into the dose and intensity of aerobic exercise in PD. Physiotherapists have important roles in advocacy and education in conjunction with care delivery to support access to evidence-based care for all people with PD.

摘要

帕金森病(PD)是目前全球增长最快的神经疾病,其患病率迅速上升,对有效医疗服务的需求也日益增加。近期研究聚焦于早期诊断及对身体功能进行积极管理的重要性。越来越多的证据表明,在临床诊断之前,许多人就已存在身体活动水平下降和轻度临床前残疾的情况,这种情况可能会持续数年。目前全球指南建议在诊断时尽早转诊至物理治疗师处。已发现多种形式的运动对早期和中期疾病的一系列运动及非运动症状均有益处。纵向研究的证据证实,长期坚持规律运动可延缓残疾的发生。如今,运动与药物治疗相结合,已被视为治疗的重要组成部分。当代物理治疗干预措施现正将健康行为改变技术与体育锻炼相结合,以促进长期运动依从性的养成。技术和数字健康领域发展迅速,目前为远程评估与监测、远程运动监督以及通过反馈和激励策略支持依从性提供了机会。近期的生物医学发现预示着帕金森病的诊断将更早、更准确,从而为早期干预创造机会。目前正在进行的研究将为帕金森病有氧运动的剂量和强度提供重要见解。物理治疗师在宣传、教育以及提供护理方面发挥着重要作用,以支持所有帕金森病患者获得循证护理。

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