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机器人辅助与电视辅助微创食管癌切除术的围手术期及中期结果:842例患者的回顾性倾向匹配分析

Perioperative and mid-term outcomes of robotic-assisted versus video-assisted minimally invasive esophagectomy for esophageal cancer: a retrospective propensity-matched analysis of 842 patients.

作者信息

Huang Jiang-Shan, Zhu Jia-Fu, Zhong Qi-Hong, Guo Fei-Long, Lin Yu-Kang, Zhang Zhen-Yang, Lin Jiang-Bo

机构信息

Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, China.

Clinical Research Center for Thoracic Tumors of Fujian Province, Fuzhou, China.

出版信息

Front Oncol. 2024 Aug 27;14:1447393. doi: 10.3389/fonc.2024.1447393. eCollection 2024.

Abstract

AIM

Comparing the safety, effectiveness, and mid-term survival rates of robot-assisted minimally invasive esophagectomy (RAMIE) and video-assisted minimally invasive esophagectomy (VAMIE).

METHODS

A total of 842 patients undergoing minimally invasive esophagectomy were analyzed, including 694 patients in VAMIE group and 148 in RAMIE group. PSM analysis was applied to generate matched pairs for further comparison. Operative outcomes, postoperative complications and Mid-term outcomes were compared between all patients in matched groups.

RESULTS

After 1:4 PSM, 148 patients in the RAMIE and 592 patients in the VAMIE. Compared to VAMIE, RAMIE exhibited earlier removal of chest and neck drainage tubes, shorter postoperative hospital stays, and a higher number of lymph node dissections. However, the surgical duration of RAMIE was longer than that of VAMIE. Postoperative complications were no statistically significant between the RAMIE and VAMIE groups. There was no statistically significant difference in the 3-year OS and DFS between the two groups.

CONCLUSION

Compared to VAMIE, RAMIE emerges as a viable and safe surgical approach and suggests RAMIE as a potential alternative to minimally invasive esophagectomy.

摘要

目的

比较机器人辅助微创食管切除术(RAMIE)与电视辅助微创食管切除术(VAMIE)的安全性、有效性和中期生存率。

方法

对总共842例行微创食管切除术的患者进行分析,其中VAMIE组694例,RAMIE组148例。应用倾向评分匹配(PSM)分析生成匹配对以进行进一步比较。对匹配组中的所有患者比较手术结果、术后并发症和中期结果。

结果

经过1:4的PSM后,RAMIE组有148例患者,VAMIE组有592例患者。与VAMIE相比,RAMIE的胸段和颈部引流管拔除时间更早,术后住院时间更短,淋巴结清扫数量更多。然而,RAMIE的手术时间比VAMIE长。RAMIE组和VAMIE组术后并发症无统计学差异。两组之间的3年总生存期(OS)和无病生存期(DFS)无统计学差异。

结论

与VAMIE相比,RAMIE是一种可行且安全的手术方法,提示RAMIE可作为微创食管切除术的一种潜在替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7f3/11385285/a96f862462a0/fonc-14-1447393-g001.jpg

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