Cai Qing, Li Mengya, Li Guifeng, Xu Xin, Li Cheng, Li Qifang
Department of Anesthesiology and Perioperative Medicine, Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Front Psychiatry. 2024 Aug 27;15:1440026. doi: 10.3389/fpsyt.2024.1440026. eCollection 2024.
To examine the effectiveness of one-week inpatient cognitive behavioral therapy for insomnia (CBT-I) in patients without severe mental disorders in the real-world setting to answer the research question "Can inpatient CBT-I be abbreviated?".
In this retrospective, single-group, pretest-posttest study, the clinical outcome data of 94 patients who underwent one-week inpatient CBT-I were collected. Self-report scale scores and hypnotic medication use were obtained at baseline and at the 3-month follow-up after therapy.
CBT-I significantly improved insomnia severity ( = -7.65, < 0.001, Cohen's 1.34), anxiety ( = -6.23, < 0.001, Cohen's 1.02), depression ( = -6.42, < 0.001, Cohen's 1.06), daytime sleepiness ( = -2.40, = 0.016, Cohen's 0.35), and fatigue severity ( = -5.54, < 0.001, Cohen's 0.88) and reduced hypnotic medication use ( = 33.62, < 0.001). At the follow-up assessment, 58 patients (67.4%) had clinically meaningful changes in insomnia, and 51 patients (59.3%) met the criteria for insomnia remission.
The results of this preliminary study imply that one-week inpatient CBT-I may be an effective intervention for the treatment of insomnia in patients without severe mental disorders.
在现实环境中检验为期一周的住院认知行为疗法治疗失眠(CBT-I)对无严重精神障碍患者的有效性,以回答“住院CBT-I能否缩短疗程?”这一研究问题。
在这项回顾性单组前后测研究中,收集了94例接受为期一周住院CBT-I治疗患者的临床结局数据。在基线期及治疗后3个月随访时获取自我报告量表评分及催眠药物使用情况。
CBT-I显著改善了失眠严重程度(=-7.65,<0.001,科恩d值为1.34)、焦虑(=-6.23,<0.001,科恩d值为1.02)、抑郁(=-6.42,<0.001,科恩d值为1.06)、日间嗜睡(=-2.40,=0.016,科恩d值为0.35)和疲劳严重程度(=-5.54,<0.001,科恩d值为0.88),并减少了催眠药物的使用(=33.62,<0.001)。在随访评估中,58例患者(67.4%)在失眠方面有临床意义的变化,51例患者(59.3%)符合失眠缓解标准。
这项初步研究结果表明,为期一周的住院CBT-I可能是治疗无严重精神障碍患者失眠的有效干预措施。