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巴西绿蜂胶治疗慢性溃疡的效果:一项随机临床试验。

Effect of Brazilian green propolis in chronic ulcer treatment: a randomized clinical trial.

机构信息

Faculdade de Medicina do ABC. Santo André, São Paulo, Brazil.

Universidade Federal de São Paulo. São Paulo, São Paulo, Brazil.

出版信息

Rev Bras Enferm. 2024 Sep 6;77(4):e20230418. doi: 10.1590/0034-7167-2023-0418. eCollection 2024.

Abstract

OBJECTIVE

to assess the effectiveness of 5% Brazilian green propolis (ointment) in individuals with chronic ulcers.

METHODS

a randomized clinical trial, developed with 40 patients randomized equally to control group (treated with essential fatty acid) and experimental group (treated with 5% green propolis) for 30 days. The outcomes of interest were sociodemographic, clinical and laboratory characteristics, lesion characteristics, such as type of tissue in the bed, presence of exudate, edge characteristics, microbial content and pain.

RESULTS

regarding sociodemographic, clinical and laboratory characteristics, the two groups did not show statistically significant differences. After assessment in 30 days, an effect was observed for both treated groups, but for the experimental group, greater effectiveness in terms of the type of tissue in the bed, type of exudate, edge characteristics, microbial content and pain.

CONCLUSION

propolis-based ointment showed a healing effect, presenting itself as a potential tool in healing chronic ulcers.

摘要

目的

评估 5%巴西绿蜂胶(软膏)在慢性溃疡患者中的疗效。

方法

一项随机临床试验,共纳入 40 名患者,随机分为对照组(用必需脂肪酸治疗)和实验组(用 5%绿蜂胶治疗),治疗时间为 30 天。主要结局指标为社会人口学、临床和实验室特征、病变特征,如床组织类型、渗出物存在、边缘特征、微生物含量和疼痛。

结果

两组在社会人口学、临床和实验室特征方面无统计学差异。治疗 30 天后,两组均有疗效,但实验组在床组织类型、渗出物类型、边缘特征、微生物含量和疼痛方面的疗效更好。

结论

基于蜂胶的软膏显示出愈合效果,可作为治疗慢性溃疡的潜在工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e4c/11382678/20fea7ca915d/0034-7167-reben-77-04-e20230418-gf01.jpg

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