Department of Physical Education, College of Education, Seoul National University, Seoul, Republic of Korea.
Department of Physical Education, Korea Air Force Academy, Cheongju, Republic of Korea.
J Sports Sci. 2024 Aug;42(16):1529-1537. doi: 10.1080/02640414.2024.2400807. Epub 2024 Sep 11.
To examine the independent and combined association of resting heart rate (RHR) and physical activity (PA) with risk of cardiovascular disease (CVD) mortality. RHR was categorized as < 60, 60-69, 70-79, and ≥ 80 bpm. Meeting PA guidelines was defined as ≥ 150 min/week of moderate to vigorous physical activity (MVPA). Cox proportional hazard models were used to calculate hazard ratios (HRs) for CVD mortality associated with RHR and PA. Among 31,697 participants, 311 CVD deaths occurred during 9.2 years of follow-up. Compared to RHR of 60-69 bpm, the risk of CVD mortality was higher in RHR of < 60 bpm (HR, 1.48; 95% CI, 1.05-2.10) and ≥ 80 bpm (HR, 1.42; 95% CI, 1.06-1.91). Participants who met PA guidelines had a lower risk of CVD mortality (HR, 0.59; 95% CI, 0.44-0.78). Among physically inactive adults compared to participants in RHR of 60-69 bpm with meeting PA guidelines, the adjusted HR for CVD mortality was 2.41 (95% CI, 1.42-4.08) for RHR of < 60 bpm, 1.59 (95% CI, 1.01-2.49) for RHR of 60-69 bpm, 1.98 (95% CI, 1.23-3.20) for RHR of 70-79 bpm and 2.41 (95% CI, 1.50-3.89) for RHR of ≥ 80 bpm Exceeding the minimum level of PA guidelines may attenuate the risk of CVD mortality associated with RHR.
为了研究静息心率（RHR）和体力活动（PA）与心血管疾病（CVD）死亡率的独立和联合关联。RHR 分为<60、60-69、70-79 和≥80 bpm。达到 PA 指南标准定义为每周至少进行 150 分钟的中度到剧烈体力活动（MVPA）。使用 Cox 比例风险模型计算与 RHR 和 PA 相关的 CVD 死亡率的危险比（HR）。在 31697 名参与者中，9.2 年的随访期间发生了 311 例 CVD 死亡。与 RHR 为 60-69 bpm 相比，RHR<60 bpm（HR，1.48；95%CI，1.05-2.10）和≥80 bpm（HR，1.42；95%CI，1.06-1.91）的 CVD 死亡率风险更高。达到 PA 指南的参与者 CVD 死亡率风险较低（HR，0.59；95%CI，0.44-0.78）。与不活跃的成年人相比，与达到 PA 指南的 RHR 为 60-69 bpm 的参与者相比，RHR<60 bpm 的 CVD 死亡率调整后的 HR 为 2.41（95%CI，1.42-4.08），RHR 为 60-69 bpm 的 HR 为 1.59（95%CI，1.01-2.49），RHR 为 70-79 bpm 的 HR 为 1.98（95%CI，1.23-3.20），RHR 为≥80 bpm 的 HR 为 2.41（95%CI，1.50-3.89）。超过 PA 指南的最低水平可能会降低与 RHR 相关的 CVD 死亡率的风险。
