Ishisaka Yoshiko, Ankam Jyoti, Feldman Jonathan, Busse Paula, Wisnivesky Juan P, Federman Alex D
Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Morningside and West, New York, NY, USA.
Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
J Asthma. 2025 Feb;62(2):354-361. doi: 10.1080/02770903.2024.2403742. Epub 2024 Sep 19.
Short-acting Beta-adrenergic Receptor Agonists (SABA) carry a risk of worse asthma outcomes when overused. Beliefs about asthma controller medications are associated with medication-taking behaviors in older adults, but the association of medication beliefs with SABA use has not been previously examined. We aimed to investigate the association of asthma and controller medication beliefs with SABA use among older patients with asthma.
We performed a cross-sectional analysis of data on adults ≥ 60 years old with moderate to severe asthma in New York City, NY ( = 234). SABA overuse was defined as the average of ≥1 inhalation per day and controller medication adherence as ≥80% of expected inhalations, measured electronically. Illness and medication beliefs were measured using the Brief-Illness Perception Questionnaire and Beliefs about Medications Questionnaire, respectively. The associations of medication-taking behaviors with beliefs were examined in multivariable logistic regression models.
The mean age was 67.6 ± 6.5 years, 84% were female, 26% were Black and 53% were Hispanic. 35% of participants overused SABA and 21% had adequate controller medication adherence. Overuse of SABA was not significantly associated with controller medication beliefs (Necessity: odds ratio [OR] 1.04, 95% confidence interval [CI] [0.97-1.12], = 0.28, Concerns: OR 0.95 [95% CI 0.88, 1.03], = 0.23) or asthma beliefs (OR 1.06 [95% CI 0.99, 1.15], = 0.11). SABA overuse was also not significantly associated with controller medication adherence (OR 2.20 [95% CI 0.88, 5.51], = 0.09).
SABA overuse was common among older adults with asthma and was not significantly associated with asthma controller medication or illness beliefs.
短效β-肾上腺素能受体激动剂（SABA）过度使用时会有导致哮喘预后更差的风险。关于哮喘控制药物的认知与老年人的用药行为有关，但用药认知与SABA使用之间的关联此前尚未得到研究。我们旨在调查老年哮喘患者中哮喘及控制药物认知与SABA使用之间的关联。
我们对纽约市年龄≥60岁的中重度哮喘成人患者（n = 234）的数据进行了横断面分析。SABA过度使用定义为每天平均吸入≥1次，控制药物依从性定义为电子测量的预期吸入量的≥80%。疾病和用药认知分别使用简明疾病认知问卷和用药认知问卷进行测量。在多变量逻辑回归模型中检验用药行为与认知之间的关联。
平均年龄为67.6±6.5岁，84%为女性，26%为黑人，53%为西班牙裔。35%的参与者过度使用SABA，21%的参与者控制药物依从性良好。SABA过度使用与控制药物认知（必要性：比值比[OR] 1.04，95%置信区间[CI] [0.97 - 1.12]，P = 0.28；担忧：OR 0.95 [95% CI 0.88, 1.03]，P = 0.23）或哮喘认知（OR 1.
