Department of Radiology, CHA Bundang Medical Center, CHA University School of Medicine, 59 Yatap-Ro, Bundang-Gu, Seongnam, 13496, Korea.
Radiol Med. 2024 Nov;129(11):1587-1596. doi: 10.1007/s11547-024-01888-7. Epub 2024 Sep 11.
To investigate the association between metabolic syndrome and perirenal fat stranding (PRFS), which is defined as linear or curvilinear soft tissue densities in the perirenal fat on computed tomography (CT).
Adults who had abdominal CT for health screening at a single institution between October 2022 and March 2023 were included retrospectively. Two radiologists assessed the extent of PRFS for each CT and graded it as absent, mild/moderate, and severe. Logistic regression analyses were used to investigate the associations between PRFS and metabolic syndrome-related factors, as well as age and gender.
Among 701 participants (mean age, 56.8 years ± 9.7; 336 women and 365 men), 87 (12.4%) had mild (n = 80) or moderate (n = 7) PRFS. None had severe PRFS. The presence of PRFS was independently associated with higher body mass index (odds ratio [OR], 2.561 and 9.842 for overweight and obese, respectively; p ≤ 0.001), elevated blood pressure with or without anti-hypertensive medication (OR, 2.232; p = 0.015), anti-diabetic medication (OR, 3.129; p < 0.001), and lipid-lowering medication (OR, 1.919; p = 0.019), older age (OR, 4.545 and 9.109 for 50-59 years and ≥ 60 years, respectively; p ≤ 0.002), and male gender (OR, 10.065; p < 0.001). Sixty three of 87 (72.4%) participants with PRFS had metabolic syndrome, while 265 of 614 (43.2%) participants without PRFS did (p < 0.001).
Incidental mild or moderate PRFS may be associated with the presence of metabolic syndrome or related disorders in otherwise healthy adults.
研究代谢综合征与肾周脂肪条纹（PRFS）之间的关系，PRFS 是指在 CT 上肾周脂肪中出现线性或曲线状软组织密度。
回顾性纳入 2022 年 10 月至 2023 年 3 月期间在一家机构进行健康筛查的腹部 CT 检查的成年人。两名放射科医生评估了每例 CT 检查的 PRFS 程度，并将其分为无、轻度/中度和重度。采用 logistic 回归分析方法研究 PRFS 与代谢综合征相关因素，以及年龄和性别之间的关系。
在 701 名参与者（平均年龄 56.8 ± 9.7 岁，女性 336 名，男性 365 名）中，87 名（12.4%）存在轻度（n=80）或中度（n=7）PRFS。无重度 PRFS。存在 PRFS 与较高的体重指数（超重和肥胖的比值比[OR]分别为 2.561 和 9.842；p≤0.001）、伴有或不伴有降压药物的高血压（OR，2.232；p=0.015）、抗糖尿病药物（OR，3.129；p<0.001）和降脂药物（OR，1.919；p=0.019）独立相关，与年龄较大（50-59 岁和≥60 岁的 OR 分别为 4.545 和 9.109；p≤0.002）和男性（OR，10.065；p<0.001）独立相关。87 名存在 PRFS 的患者中有 63 名（72.4%）患有代谢综合征，而 614 名无 PRFS 的患者中有 265 名（43.2%）患有代谢综合征（p<0.001）。
在其他方面健康的成年人中，偶然出现的轻度或中度 PRFS 可能与代谢综合征或相关疾病的存在有关。
