Division of Cellular & Molecular Biology, Diabetes Research Group, Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, ON M5G 1L7, Canada.
Division of Cellular & Molecular Biology, Diabetes Research Group, Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, ON M5G 1L7, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada.
Immunity. 2024 Sep 10;57(9):2010-2012. doi: 10.1016/j.immuni.2024.08.010.
Chronic inflammation is considered a hallmark of aging. In a recent issue of Nature, Widjaja et al. examined genetic and pharmacologic inhibition of interleukin (IL)-11 on aging pathology and found that inhibiting IL-11 signaling increases lifespan and healthspan in mice.
慢性炎症被认为是衰老的一个标志。在最近的一期《自然》杂志上，Widjaja 等人研究了白细胞介素 (IL)-11 的遗传和药理学抑制对衰老病理的影响，发现抑制 IL-11 信号通路可以增加小鼠的寿命和健康寿命。
