Smith Glenys, Crago Anna-Louise, Alexandre Stephanie, Gravel-Tropper Denise, Isada Melissa, Knight Braden, Mackenzie Jami, Shurgold Jayson
Antimicrobial Resistance Task Force, Public Health Agency of Canada.
Can Commun Dis Rep. 2024 Sep 5;50(9):312-325. doi: 10.14745/ccdr.v50i09a04. eCollection 2024 Sep.
Antimicrobial use (AMU) is a known driver of antimicrobial resistance. Insight into prevalence and correlates of AMU can help identify health inequities and areas for targeted action. To better understand sociodemographic and medical dimensions of AMU in Canada, the Public Health Agency of Canada, in partnership with Statistics Canada, developed a Rapid Response Module questionnaire on self-reported oral antibiotic use, to be administered as part of the 2018 Canadian Community Health Survey (CCHS).
To provide data on the proportion of people in Canada that self-report the use of antibiotics and sociodemographic and health factors associated with use.
This cross-sectional study used data from the CCHS, a national survey of 24,176 people with a clustered multi-stage stratified random sampling design. In 2018, an antibiotic use module was administered to CCHS participants.
Among respondents 18 years and older, 26% reported receipt of at least one oral antibiotic over the past year. Several sociodemographic and health factors had higher adjusted odds of receiving an antibiotic prescription, including those aged 18 years compared to aged 48 years (mean), women compared to men, immigrants compared to non-immigrants (excluding Indigenous), current and former smokers compared to those who have never smoked, and those with comorbidities (asthma, chronic obstructive pulmonary disease, arthritis, heart disease, cancer, bowel disorder and urinary incontinence).
Variations in AMU across different key populations and sociodemographic groups highlight the need to improve our understanding of different drivers of AMU and for tailored interventions to reduce inequitable risks of antimicrobial resistance.
抗菌药物的使用是已知的抗菌药物耐药性驱动因素。深入了解抗菌药物使用的流行情况及其相关因素有助于识别健康不平等现象和确定有针对性的行动领域。为了更好地了解加拿大抗菌药物使用的社会人口统计学和医学层面，加拿大公共卫生局与加拿大统计局合作，编制了一份关于自我报告的口服抗生素使用情况的快速反应模块问卷，作为2018年加拿大社区健康调查（CCHS）的一部分进行发放。
提供有关加拿大自我报告使用抗生素的人群比例以及与使用相关的社会人口统计学和健康因素的数据。
这项横断面研究使用了CCHS的数据，该调查采用整群多阶段分层随机抽样设计，对24176人进行了全国性调查。2018年，向CCHS参与者发放了抗生素使用模块问卷。
在18岁及以上的受访者中，26%报告在过去一年中至少接受过一次口服抗生素治疗。几个社会人口统计学和健康因素与接受抗生素处方的调整后较高几率相关，包括18岁人群与48岁人群（平均年龄）相比、女性与男性相比、移民与非移民（不包括原住民）相比、当前和以前吸烟者与从不吸烟者相比，以及患有合并症（哮喘、慢性阻塞性肺疾病、关节炎、心脏病、癌症、肠道疾病和尿失禁）的人群。
不同关键人群和社会人口统计学群体之间抗菌药物使用情况的差异凸显了需要更好地了解抗菌药物使用的不同驱动因素，并采取针对性干预措施以降低抗菌药物耐药性的不公平风险。
