Seuc A H, Mirabal-Sosa M, Garcia-Serrano Y, Alfonso-Sague K, Fernandez-Gonzalez L
Instituto Nacional de Higiene, Epidemiología y Microbiología (INHEM), Infanta 1151, e/ Clavel y Llinas, Centro Habana, La Habana, 10300, Cuba.
Public Health Pract (Oxf). 2024 Aug 22;8:100537. doi: 10.1016/j.puhip.2024.100537. eCollection 2024 Dec.
To estimate the national and provincial number of excess deaths due to diabetes across Cuba in 2019.
Cross-sectional design with secondary data.
We used DISMODII, a computerized generic disease model, to assess disease burden by modelling the relationships between incidence, prevalence, and disease-specific mortality. Baseline input data included population structure, total mortality, and age- and sex-specific estimates for diabetes prevalence from the Cuban National Health Survey 2019, and available published estimates of the relative risk of death for people with diabetes compared to people without diabetes. The results were internally validated with DISMODII output for duration of diabetes (years).
In 2019, we estimated an excess of mortality attributable to diabetes of 7.5 times the diabetes mortality reported by the National Death Registry, which is equivalent to 16.4 % of all deaths in Cuba. The percentages of all-cause mortality among provinces varied between 10.7 % in Villa Clara and 24.5 % in Ciego de Avila.
These are the first estimates of mortality attributable to diabetes in Cuba and its provinces. Diabetes is likely to be a much more prominent leading cause of death than the 9th ranking reported by the Cuban National Death Registry 2019. Disease models similar to DISMODII are important tools to validate the epidemiologic indicators used in the burden of disease calculations.
估算2019年古巴全国及各省因糖尿病导致的超额死亡人数。
采用横断面设计及二手数据。
我们使用DISMODII(一种计算机化的通用疾病模型),通过对发病率、患病率和疾病特异性死亡率之间的关系进行建模来评估疾病负担。基线输入数据包括人口结构、总死亡率、来自2019年古巴全国健康调查的糖尿病患病率的年龄和性别特异性估计值,以及已发表的糖尿病患者与非糖尿病患者相比的相对死亡风险估计值。结果通过DISMODII输出的糖尿病病程(年)进行内部验证。
2019年,我们估计因糖尿病导致的超额死亡率是国家死亡登记处报告的糖尿病死亡率的7.5倍,这相当于古巴所有死亡人数的16.4%。各省全因死亡率的百分比在比亚克拉拉省的10.7%至西戈德阿维拉省的24.5%之间有所不同。
这些是古巴全国及各省因糖尿病导致的死亡率的首次估计。糖尿病可能是比古巴国家死亡登记处2019年报告的第9位更为突出的主要死因。类似于DISMODII的疾病模型是验证疾病负担计算中使用的流行病学指标的重要工具。