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三尖瓣反流患者的医疗保健利用与支出:一项基于人群的队列研究。

Healthcare utilization and expenditures in patients with tricuspid regurgitation: A population-based cohort study.

作者信息

Chung Ching-Hu

机构信息

Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.

出版信息

Int J Cardiol Heart Vasc. 2024 Aug 22;54:101495. doi: 10.1016/j.ijcha.2024.101495. eCollection 2024 Oct.

DOI:10.1016/j.ijcha.2024.101495
PMID:39263411
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11387262/
Abstract

BACKGROUND

Tricuspid regurgitation (TR) is the most common tricuspid valve (TV) condition. However, little is known about the prevalence, clinical significance, or economic impact of TR, including TR with comorbid heart failure (HF).

MATERIALS AND METHODS

Taiwan's National Health Insurance Research Database was used to perform a retrospective cohort study about patients with TR. The study included patients over the age of 18 with TR who provided data from January 2017 to December 2019. The cohorts were divided into six groups based on whether significant TR was present (sTR) or not (nsTR), and whether HF was present (HF) or not present (noHF), or inconclusive (incHF).

RESULTS

This study included 21,051 patients with TR. Patients with nsTR-noHF had an annualized healthcare burden of 0.36 all-cause hospitalizations, 3.26 days length of stay (LOS), and NTD 66,834 in expenses. sTR led to significant increases in healthcare utilization and expenditures. The annualized economic burden for sTR-noHF patients increased to 1.03 all-cause hospitalizations, 10.75 days LOS, and NTD 210,842 in expenses. Patients with sTR and HF had significantly higher healthcare utilization and expenditures; patients with sTR-HF had an annualized economic burden of 2.46 all-cause hospitalizations, 33.18 days LOS, and NTD 480,711 in spending.

CONCLUSION

TR patients with HF or sTR are more likely to be hospitalized, use more healthcare resources, and face higher financial burdens.

摘要

背景

三尖瓣反流(TR)是最常见的三尖瓣疾病。然而,对于TR的患病率、临床意义或经济影响,包括合并心力衰竭(HF)的TR,人们了解甚少。

材料与方法

利用台湾国民健康保险研究数据库对TR患者进行回顾性队列研究。该研究纳入了2017年1月至2019年12月期间提供数据的18岁以上TR患者。根据是否存在严重TR(sTR)或无严重TR(nsTR),以及是否存在HF(HF)或无HF(noHF)或不确定(incHF),将队列分为六组。

结果

本研究纳入了21,051例TR患者。nsTR-noHF患者的全因住院年度医疗负担为0.36次,住院时长为3.26天,费用为新台币66,834元。sTR导致医疗利用率和支出显著增加。sTR-noHF患者的年度经济负担增加到全因住院1.03次,住院时长10.75天,费用为新台币210,842元。合并sTR和HF的患者医疗利用率和支出显著更高;sTR-HF患者的年度经济负担为全因住院2.46次,住院时长33.18天,支出为新台币480,711元。

结论

合并HF或sTR的TR患者更有可能住院,使用更多医疗资源,并面临更高的经济负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989a/11387262/ad12b6c26674/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989a/11387262/ad12b6c26674/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989a/11387262/ad12b6c26674/gr1.jpg

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本文引用的文献

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Tricuspid valve regurgitation: current diagnosis and treatment.三尖瓣反流:当前的诊断与治疗
Am J Cardiovasc Dis. 2022 Feb 15;12(1):1-18. eCollection 2022.
2
Functional Tricuspid Regurgitation and Right Atrial Remodeling in Heart Failure With Preserved Ejection Fraction.射血分数保留的心力衰竭中的功能性三尖瓣反流和右心房重构。
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Secondary Tricuspid Regurgitation: Pathophysiology, Incidence and Prognosis.继发性三尖瓣反流:病理生理学、发病率及预后
Front Cardiovasc Med. 2021 Jul 22;8:701243. doi: 10.3389/fcvm.2021.701243. eCollection 2021.
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Transcatheter Tricuspid Valve Annuloplasty: Show Me the Real-World Data.
Circ Cardiovasc Interv. 2021 Aug;14(8):e011018. doi: 10.1161/CIRCINTERVENTIONS.121.011018. Epub 2021 Jul 30.
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Healthcare utilization in clinically significant tricuspid regurgitation patients with and without heart failure.有和没有心力衰竭的临床显著三尖瓣反流患者的医疗保健利用。
J Comp Eff Res. 2021 Jan;10(1):29-37. doi: 10.2217/cer-2020-0198. Epub 2020 Nov 11.
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The economic impact of clinically significant tricuspid regurgitation in a large, administrative claims database.在大型行政索赔数据库中,临床显著三尖瓣反流的经济影响。
J Med Econ. 2020 May;23(5):521-528. doi: 10.1080/13696998.2020.1718681. Epub 2020 Mar 2.
7
1-Year Outcomes After Edge-to-Edge Valve Repair for Symptomatic Tricuspid Regurgitation: Results From the TriValve Registry.Edge-to-Edge 瓣叶修复术治疗症状性三尖瓣反流的 1 年结果:TriValve 注册研究结果。
JACC Cardiovasc Interv. 2019 Aug 12;12(15):1451-1461. doi: 10.1016/j.jcin.2019.04.019.
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Excess Mortality Associated With Functional Tricuspid Regurgitation Complicating Heart Failure With Reduced Ejection Fraction.射血分数降低的心力衰竭合并功能性三尖瓣反流与死亡率升高相关。
Circulation. 2019 Jul 16;140(3):196-206. doi: 10.1161/CIRCULATIONAHA.118.038946. Epub 2019 May 23.
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Natural History of Functional Tricuspid Regurgitation: Implications of Quantitative Doppler Assessment.功能性三尖瓣反流的自然病史:定量多普勒评估的意义。
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