Oral Health Prev Dent. 2024 Sep 12;22:453-458. doi: 10.3290/j.ohpd.b5740308.
To evaluate the antimicrobial effect of a new active oxygen fluid (Blue®m) as a root canal irrigant against Enterococcus faecalis compared to sodium hypochlorite (NaOCl).
Forty-five extracted single-canaled human teeth were selected, received root canal preparation, autoclaved, and contaminated with Enterococcus faecalis. The specimens were randomly allocated into three groups: Group (A) served as the negative control, receiving irrigation with saline (n = 15); Group (B) was irrigated with 5.25% NaOCl (n = 15); and Group (C) was irrigated with 10 mL of Blue®m (n = 15). Microbial sampling from the root canals was performed before and after irrigation. The difference between the pre-irrigation and post-irrigation colony-forming units (CFU/mL) was calculated. The data was analysed using a one-way ANOVA followed by post-hoc Tukey tests. The significance level was set at 5%.
Blue®m statistically significantly reduced the bacterial load compared to saline (p = 0.009), but NaOCl was most effective, outperforming both (p 0.0001).
Irrigation with Blue®m demonstrated antibacterial efficacy against Enterococcus faecalis, but it was not as effective as NaOCl.
评估一种新型活性氧液(Blue®m)作为根管冲洗剂对粪肠球菌的抗菌效果,与次氯酸钠(NaOCl)相比。
选择 45 颗已提取的单根管人牙,进行根管预备、高压灭菌并污染粪肠球菌。将标本随机分为三组:A 组为阴性对照组,用生理盐水冲洗(n=15);B 组用 5.25% NaOCl 冲洗(n=15);C 组用 10 mL Blue®m 冲洗(n=15)。冲洗前后从根管中取样微生物。计算冲洗前后的菌落形成单位(CFU/mL)差异。采用单因素方差分析,随后进行 Tukey 事后检验。显著性水平设定为 5%。
与生理盐水相比,Blue®m 统计学上显著降低了细菌负荷(p=0.009),但次氯酸钠效果最佳,优于两者(p=0.0001)。
Blue®m 冲洗对粪肠球菌具有抗菌效果,但不如次氯酸钠有效。