49岁以上健康人群心电图异常的患病率和发病率

[Prevalence and incidence of electrocardiographic abnormalities in healthy population older than 49].

作者信息

Alventosa Zaidin M, Alzamora Sas M T, Pera Blanco G, López-Lifante V M, Mengual-Miralles N, Toran Monserrat P

机构信息

Centre d'Atenció Arenys de Mar, Gerència d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Arenys de Mar, Barcelona, España.

Centre Riu Nord-Riu Sud, Gerència d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Santa Coloma de Gramenet, Barcelona, España; Unitat de Suport a la Recerca Metropolitana Nord, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Barcelona, España.

出版信息

Semergen. 2024 Nov-Dec;50(8):102318. doi: 10.1016/j.semerg.2024.102318. Epub 2024 Sep 11.

DOI:10.1016/j.semerg.2024.102318

PMID:39265247

Abstract

PURPOSE

To determine the prevalence and incidence of electrocardiographic abnormalities (EKG-abn).

MATERIAL AND METHODS

Design. 2 stage study: 1st: descriptive cross-sectional, 2nd: prospective cohort.

LOCATION

28 urban primary health centers in Barcelona city area.

PARTICIPANTS

The study population was composed by patients who had participated in the population based ARTPER multicentric study. This study has two phases where each patient had one EKG, physical examination and blood test to obtain the secondary variables. The available EKG from both phases were reviewed, achieving a total of 2,727 patients with EKG. 601 (22%) individuals with CV disease were excluded. A total of 2.126 patients were studied of whom 392 (18%) had 2 EKG, one at each phase. Mean measurements. The association between the presence of EKG-abn and explanatory variables was performed using multivariate logistic regression, obtaining odds ratios (OR) and their 95% confidence intervals (95%CI).

RESULTS

58% women and average age 66years. 32% (95%CI: 30%-34%) (n=671) presented EKG-abn of whom 60% (n=402) were minor and 40% (n=269) major disorders. The most common EKG-abn were the conduction disturbances. EKG-abn were associated with males (OR: 1.7; 95%CI: 1.4-2.1) and patients older than 65 (OR: 1.6; 95%CI: 1.4-2.0). Among the 345 people without EKG-abn at baseline and with 2 available EKG, 71 showed an EKG-abn at the second EKG (incidence in 4.7years of 21% (95%CI: 16%-25%).

CONCLUSION

EKG abnormalities are common in healthy general population. EKG-abn are more common in male and elderly patients.

摘要

目的

确定心电图异常（EKG-abn）的患病率和发病率。

材料与方法

设计。两阶段研究：第一阶段：描述性横断面研究；第二阶段：前瞻性队列研究。

地点

巴塞罗那市区的28个城市初级卫生保健中心。

参与者

研究人群由参与基于人群的ARTPER多中心研究的患者组成。该研究有两个阶段，每位患者进行一次心电图检查、体格检查和血液检测以获取次要变量。对两个阶段的可用心电图进行了回顾，共获得2727例有心电图检查结果的患者。排除601例（22%）患有心血管疾病的个体。共研究了2126例患者，其中392例（18%）在每个阶段各有一次心电图检查。均值测量。使用多因素逻辑回归分析心电图异常与解释变量之间的关联，得出比值比（OR）及其95%置信区间（95%CI）。

结果

女性占58%，平均年龄66岁。32%（95%CI：30%-34%）（n = 671）存在心电图异常，其中60%（n = 402）为轻度异常，40%（n = 269）为重度异常。最常见的心电图异常是传导障碍。心电图异常与男性（OR：1.7；95%CI：1.4 - 2.1）和65岁以上患者（OR：1.6；95%CI：1.4 - 2.0）相关。在基线时无心电图异常且有两次可用心电图的345人中，71人在第二次心电图检查时出现心电图异常（4.7年的发病率为21%（95%CI：16%-25%））。