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Determination of HBV DNA by a simplified method of spot hybridization.

作者信息

Gmelin K, Theilmann L, Will H, Czygan P, Doerr H W, Kommerell B

出版信息

Hepatogastroenterology. 1985 Jun;32(3):117-20.

PMID:3926615
Abstract

Molecular hybridization was employed to detect HBV DNA in sera of patients with acute or chronic hepatitis, by a simplified version of the spot hybridization technique. HBV DNA was found in 21 out of 50 sera obtained in acute hepatitis B. Determination of HBV DNA was negative in sera of patients with hepatitis A, Epstein-Bar virus infections or other HBsAg-negative liver diseases. There was no cross-hybridization between HBV DNA and sera of patients with non-A, non-B hepatitis.

摘要

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引用本文的文献

1
Assay of hepatitis B virus genome titers in sera of infected subjects.感染受试者血清中乙肝病毒基因组滴度的检测
Eur J Clin Microbiol. 1986 Jun;5(3):330-5. doi: 10.1007/BF02017791.
2
Infectivity of medical staff for hepatitis B.医务人员对乙型肝炎的传染性
Infection. 1988 May-Jun;16(3):171-4. doi: 10.1007/BF01644095.
3
Pattern and duration of HBV DNA seropositivity in acute hepatitis B.急性乙型肝炎中HBV DNA血清学阳性的模式及持续时间
Dig Dis Sci. 1988 Apr;33(4):477-80. doi: 10.1007/BF01536035.