法氏囊：环境抗原的捕获部位。
The bursa of Fabricius: a trapping site for environmental antigens.
作者信息
Ekino S, Suginohara K, Urano T, Fujii H, Matsuno K, Kotani M
出版信息
Immunology. 1985 Jul;55(3):405-10.
Abstract
The entry of environmental antigens into the lumen of the bursa of Fabricius was prevented by ligating the bursal duct prior to hatching (BDL: bursal duct ligation). The development of 'natural' serum agglutinins for bacteria and heteroerythrocytes was markedly suppressed by BDL. The antigen-specific recovery was observed by simultaneous administration of sterile antigens into the bursal lumen at the time of BDL. These results strongly suggest that the bursa of Fabricius is a major channel through which environmental antigens stimulate the immune system and induce the formation of 'natural' serum agglutinins.
摘要
在孵化前结扎法氏囊导管可阻止环境抗原进入法氏囊腔（BDL：法氏囊导管结扎）。法氏囊导管结扎显著抑制了针对细菌和异种红细胞的“天然”血清凝集素的发育。在法氏囊导管结扎时，通过向法氏囊腔内同时注入无菌抗原观察到了抗原特异性恢复。这些结果有力地表明，法氏囊是环境抗原刺激免疫系统并诱导“天然”血清凝集素形成的主要通道。
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本文引用的文献
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Pinocytosis by epithelium associated with lymphoid follicles in the bursa of Fabricius, appendix, and Peyer's patches. An electron microscopic study.法氏囊、阑尾和派伊尔结中与淋巴滤泡相关的上皮细胞的胞饮作用。一项电子显微镜研究。
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