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先天性心脏病患儿坏死性小肠结肠炎诊断的标准化

Standardizing the diagnosis of necrotizing enterocolitis in infants with congenital heart disease.

作者信息

Hillyer Margot, Fundora Michael, Williams Feifei, Gleason Michelle, Lukacs Mary, Hamrick Shannon, Meisel Jonathan, Clarke Shanelle, Korcinsky-Tillman Natalie, Chanani Nikhil

机构信息

Emory University School of Medicine, Department of Pediatrics, Division of Critical Care Medicine, Atlanta, GA, USA.

Emory University School of Medicine, Department of Pediatrics, Division of Cardiology, Atlanta, GA, USA.

出版信息

J Perinatol. 2024 Sep 12. doi: 10.1038/s41372-024-02112-0.

DOI:10.1038/s41372-024-02112-0
PMID:39266665
Abstract

OBJECTIVE

This quality improvement initiative aimed to standardize the diagnosis of necrotizing enterocolitis (NEC) in infants with congenital heart disease (CHD).

STUDY DESIGN

A multidisciplinary team developed clinical practice guidelines for the diagnosis and treatment of NEC within the Cardiac Intensive Care Unit (CICU). The diagnosis rate of NEC per 100 at-risk admissions was the primary outcome measure. NEC order set usage was employed as a process measure, and the balancing measures monitored were CICU length of stay (LOS) and mortality.

RESULT

After guideline development and implementation, the diagnosis rate of NEC decreased from 3% to 1%, sustained over three years. The EMR order set enabled guideline integration into daily workflow. No change was noted in CICU LOS or mortality.

CONCLUSION

Guideline implementation standardized the diagnosis of NEC in infants with CHD. Establishing a standardized definition and subsequent treatment regimen has enabled us to provide more consistent and appropriate care.

摘要

目的

这项质量改进计划旨在规范先天性心脏病(CHD)婴儿坏死性小肠结肠炎(NEC)的诊断。

研究设计

一个多学科团队制定了心脏重症监护病房(CICU)内NEC诊断和治疗的临床实践指南。每100例高危入院患者的NEC诊断率是主要结局指标。NEC医嘱集的使用作为一项过程指标,监测的平衡指标是CICU住院时间(LOS)和死亡率。

结果

在制定和实施指南后,NEC诊断率从3%降至1%,并持续了三年。电子病历医嘱集使指南能够融入日常工作流程。CICU LOS或死亡率未发现变化。

结论

指南的实施规范了CHD婴儿NEC的诊断。建立标准化定义和后续治疗方案使我们能够提供更一致和适当的护理。

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本文引用的文献

1
Order Set Usage is Associated With Lower Hospital Mortality in Patients With Sepsis.医嘱集的使用与脓毒症患者较低的医院死亡率相关。
Crit Care Explor. 2023 May 16;5(5):e0918. doi: 10.1097/CCE.0000000000000918. eCollection 2023 May.
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Management of Acute Lower Gastrointestinal Bleeding: A Survey to Assess Adherence to Guidelines Across the United Kingdom and Ireland.急性下消化道出血的管理:一项评估英国和爱尔兰对指南遵循情况的调查
Cureus. 2022 May 24;14(5):e25273. doi: 10.7759/cureus.25273. eCollection 2022 May.
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Necrotizing enterocolitis and congenital heart disease.
坏死性小肠结肠炎和先天性心脏病。
Ann Pediatr Cardiol. 2021 Oct-Dec;14(4):507-515. doi: 10.4103/apc.apc_30_21. Epub 2022 Mar 25.
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Development of necrotizing enterocolitis in full-term infants with duct dependent congenital heart disease.足月患依赖导管型先天性心脏病婴儿发生坏死性小肠结肠炎。
BMC Pediatr. 2022 Apr 2;22(1):174. doi: 10.1186/s12887-022-03186-5.
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Necrotizing Enterocolitis in Children with Congenital Heart Disease: A Literature Review.先天性心脏病患儿坏死性小肠结肠炎:文献复习。
Pediatr Cardiol. 2021 Dec;42(8):1688-1699. doi: 10.1007/s00246-021-02691-1. Epub 2021 Sep 12.
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Challenges in diagnosing necrotizing enterocolitis.诊断坏死性小肠结肠炎的挑战。
Pediatr Res. 2020 Aug;88(Suppl 1):16-20. doi: 10.1038/s41390-020-1090-4.
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Defining necrotizing enterocolitis: current difficulties and future opportunities.定义坏死性小肠结肠炎:当前的困难和未来的机遇。
Pediatr Res. 2020 Aug;88(Suppl 1):10-15. doi: 10.1038/s41390-020-1074-4.
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Antibiotic Treatments and Patient Outcomes in Necrotizing Enterocolitis.抗生素治疗与坏死性小肠结肠炎患者结局的相关性。
Am J Perinatol. 2020 Oct;37(12):1250-1257. doi: 10.1055/s-0039-1693429. Epub 2019 Jul 15.
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Implementing clinical guidelines.实施临床指南。
Pract Neurol. 2019 Dec;19(6):529-535. doi: 10.1136/practneurol-2017-001814. Epub 2019 Jun 12.
10
Necrotizing enterocolitis in patients with congenital heart disease: A single center experience.先天性心脏病患者的坏死性小肠结肠炎:单中心经验
J Pediatr Surg. 2018 May;53(5):914-917. doi: 10.1016/j.jpedsurg.2018.02.014. Epub 2018 Feb 7.