Department of Biostatistics, School of Public health, Southeast University, Nanjing, China.
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
BMC Infect Dis. 2024 Sep 12;24(1):964. doi: 10.1186/s12879-024-09764-5.
The persistent symptoms arising from COVID-19 infection pose a substantial threat to patients' health, carrying significant implications. Amidst the evolving COVID-19 control strategies in China, healthcare workers (HCWs) endure considerable stress. This study aims to evaluate the prevalence of long COVID infections and their influencing factors among primary HCWs after epidemic control policy adjustment in Jiangsu.
A self-designed questionnaire was administered through on-site surveys among primary HCWs in five counties and districts within Jiangsu Province from July 4 to July 20, 2023. Logistic regression analysis was employed to identify factors associated with long COVID.
The prevalence of long COVID among primary HCWs stood at 12.61%, with a 95% confidence interval (CI) of 11.67-13.55%. Among those affected, the most common long COVID symptoms were hypomnesia (4.90%, 95%CI: 4.29-5.51%), sleep difficulties (2.73%, 95%CI: 2.27-3.19%), fatigue (2.35%, 95%CI: 1.92-2.78%), disturbances in the reproductive system (1.93%, 95%CI: 1.54-2.32%), hair loss (1.85%, 95%CI: 1.47-2.23%), and myalgia/arthralgia (1.51%, 95%CI: 1.16-1.86%). Multivariate logistic regression revealed that older age groups (30-45 years (adjusted odds ratio (aOR) = 1.93, 95%CI: 1.44-2.58), 45-60 years (aOR = 2.82, 95%CI: 2.07-3.84)), females (aOR = 1.26, 95%CI: 1.03-1.55), and higher work stress (high stress (aOR = 1.52, 95%CI: 1.24-1.86), extremely high stress (aOR = 1.37, 95%CI: 1.03-1.82)) were more prone to long COVID. Conversely, individuals with educational attainment below the bachelor's degree (aOR = 0.67, 95%CI: 0.55-0.82) and those who received four or more doses of the COVID-19 vaccine (aOR = 0.55, 95%CI: 0.33-0.92) were at a reduced risk.
This study investigates the prevalence of long COVID among primary HCWs and identifies key influencing factors. These findings are crucial for assisting in the early identification of COVID-19 patients at risk for long-term complications, developing targeted interventions aimed at optimizing healthcare resource allocation and enhancing the work conditions and quality of life of HCWs. To mitigate the prevalence of long COVID, healthcare providers and local authorities should implement effective measures, such as optimizing work-rest schedules and actively advocating for vaccination.
新冠病毒感染后持续存在的症状对患者的健康构成重大威胁。在中国不断调整的新冠疫情防控策略中，医护人员承受着巨大的压力。本研究旨在评估江苏省疫情防控政策调整后初级医护人员中长新冠感染的流行率及其影响因素。
2023 年 7 月 4 日至 7 月 20 日，通过现场调查，在江苏省五个县（区）的初级医护人员中使用自行设计的问卷进行研究。采用 logistic 回归分析识别与长新冠相关的因素。
初级医护人员长新冠感染的流行率为 12.61%，95%置信区间（CI）为 11.67-13.55%。在受影响的人群中，最常见的长新冠症状是记忆力减退（4.90%，95%CI：4.29-5.51%）、睡眠困难（2.73%，95%CI：2.27-3.19%）、疲劳（2.35%，95%CI：1.92-2.78%）、生殖系统紊乱（1.93%，95%CI：1.54-2.32%）、脱发（1.85%，95%CI：1.47-2.23%）和肌痛/关节痛（1.51%，95%CI：1.16-1.86%）。多变量 logistic 回归显示，年龄较大的组（30-45 岁（调整后的优势比（aOR）=1.93，95%CI：1.44-2.58），45-60 岁（aOR=2.82，95%CI：2.07-3.84））、女性（aOR=1.26，95%CI：1.03-1.55）和更高的工作压力（高压力（aOR=1.52，95%CI：1.24-1.86），极高压力（aOR=1.37，95%CI：1.03-1.82））更易发生长新冠。相反，教育程度低于本科（aOR=0.67，95%CI：0.55-0.82）和接种四剂或更多剂新冠疫苗（aOR=0.55，95%CI：0.33-0.92）的个体患病风险降低。
本研究调查了初级医护人员中长新冠的流行率，并确定了关键影响因素。这些发现对于帮助早期识别有长期并发症风险的新冠病毒患者，以及制定针对医护人员的干预措施以优化医疗资源分配、改善工作条件和生活质量至关重要。为了降低长新冠的流行率，医护人员和当地卫生部门应采取有效措施，例如优化工作-休息时间安排，并积极倡导接种疫苗。
