Mbalizi Council Designated Hospital, P.O Box 6117, Mbeya, Tanzania.
School of Public Health and Social Sciences, Dar es Salaam, Muhimbili University of Health and Allied Sciences, P.O.Box 65001, Dar es Salaam, Tanzania.
BMC Public Health. 2024 Sep 12;24(1):2481. doi: 10.1186/s12889-024-19643-y.
Coronavirus Disease 2019 (COVID-19) has been associated with adverse effects and death among people with low immunity, including pregnant women. Despite introducing the vaccine as the proper means to curb the spread of the pandemic, vaccine uptake is still low. This study assessed the influence of perception, attitude, and trust toward COVID-19 vaccine uptake among pregnant women attending Antenatal Care Clinics.
A cross-sectional study design was used, utilizing a quantitative approach with a cross-sectional analytical design conducted in Mbeya urban, distribution of sample size during data collection based on client's volume at three government health facilities (one tertiary health facility, one secondary health facility, and one primary health facility) in Mbeya Urban, Tanzania. Data were collected from 333 pregnant women who attended ANC during the data collection period using a questionnaire with closed-ended questions administered to respondents face-to-face. Data cleaning and analysis were done using Excel and Stata/SE 14.1 software for bivariate and multivariate data; Pearson's chi-squire and Fisher's test were used to analyze the independent determinants of COVID-19 vaccine uptake.
The proportion of pregnant women vaccinated with the COVID-19 vaccine was 27%. There was a statistically significant association between the respondents' vaccine uptake with primary education and < 5 work experience to vaccine uptake P = 0.015 (AOR = 6.58; 95% CI; 1.45-29.85), and P = 0.046 (AOR = 2.45; 95% CI; 1.02-5.89) respectively. The association of attitude influence to COVID-19 vaccine uptake was statistically significant (acceptance of vaccine due to its availability, vaccine acceptance for protection against COVID-19 pandemic to respondent and her baby, experience from other vaccines) was statistically significant at P = 0.011 (AOR = 4.43; 95% CI; 1.41-13.93), P = 0.001 (AOR = 45.83; 95% CI; 18.6-112.89) respectively. The level of trust in the COVID-19 vaccine influenced respondents' association with vaccine uptake in the 2nd and 3rd trimesters of pregnancy (P = 0.633 (AOR = 1.23; 95% CI; 0.53-2.48), respectively.
Pregnant women's positive attitude and trust in the COVID-19 vaccine influenced them to uptake it; our conclusion supports the WHO guidelines that the COVID-19 vaccine should be administered to pregnant women since it is a safer means to curb COVID-19 pregnancy-related complications.
新型冠状病毒病 2019（COVID-19）与免疫力低下人群的不良影响和死亡有关，包括孕妇。尽管疫苗的推出是遏制大流行传播的适当手段，但疫苗接种率仍然很低。本研究评估了孕妇对 COVID-19 疫苗接种的认知、态度和信任对疫苗接种的影响，这些孕妇参加了产前保健诊所。
采用横断面研究设计，采用定量方法，采用横断面分析设计，在坦桑尼亚姆贝亚市进行。在数据收集期间，根据三家政府卫生设施（一家三级保健设施、一家二级保健设施和一家初级保健设施）的客户数量，在样本量上进行了分布。使用封闭式问卷，面对面地向 333 名在数据收集期间参加 ANC 的孕妇收集数据。使用 Excel 和 Stata/SE 14.1 软件对数据进行清理和分析，用于双变量和多变量数据；使用 Pearson's chi-squire 和 Fisher's 检验分析 COVID-19 疫苗接种的独立决定因素。
COVID-19 疫苗接种的孕妇比例为 27%。受访者的疫苗接种与以下因素之间存在统计学显著关联：接受初级教育和工作经验<5 年与疫苗接种 P=0.015（AOR=6.58；95%CI；1.45-29.85），以及 P=0.046（AOR=2.45；95%CI；1.02-5.89）。对 COVID-19 疫苗接种的态度影响的关联具有统计学意义（由于其可获得性而接受疫苗、为保护孕妇及其婴儿免受 COVID-19 大流行而接受疫苗、从其他疫苗获得的经验），具有统计学意义，P=0.011（AOR=4.43；95%CI；1.41-13.93），P=0.001（AOR=45.83；95%CI；18.6-112.89）。对 COVID-19 疫苗的信任度影响了受访者在妊娠第 2 和第 3 个月与疫苗接种的关联（P=0.633（AOR=1.23；95%CI；0.53-2.48））。
孕妇对 COVID-19 疫苗的积极态度和信任影响了她们的接种意愿；我们的结论支持世界卫生组织的指导方针，即应向孕妇接种 COVID-19 疫苗，因为这是遏制与 COVID-19 相关的妊娠并发症的更安全手段。
