Oral and Craniomaxillofacial Surgery, University Hospital Basel, Spitalstrasse 21, Basel, 4031, Switzerland.
Pediatric Maxillofacial Surgery, University Children's Hospital Basel, Spitalstrasse 33, Basel, 4031, Switzerland.
World J Surg Oncol. 2024 Sep 12;22(1):246. doi: 10.1186/s12957-024-03520-4.
Intraosseous myofibroma of the jaw is a rare neoplasm of mesenchymal origin with limited comprehensive understanding. It typically affects patients in the first two decades of life with a male predilection.
This study presents a rare case of myofibroma mimicking an odontogenic lesion in a 2-year-old boy. The patient presented with an incidental finding of a painless swelling of the right mandibular ramus of unknown etiology. Imaging analysis revealed a solid, expansile lesion adjacent to the germinal zone of the right mandibular first molar. Histopathologic analysis and immunohistochemistry after incisional biopsy suggested a possible central odontogenic fibroma, and the patient underwent total enucleation, leading to the final diagnosis of intraosseous myofibroma. Follow-up examinations showed no evidence of recurrence.
This report contributes to the understanding of myofibroma in pediatric patients and underscores the critical role of meticulous histopathologic examination for effective surgical planning and optimal patient outcomes.
颌骨内肌纤维瘤是一种起源于间叶组织的罕见肿瘤，其综合认识有限。它通常影响生命头二十年的男性患者。
本研究报告了一例罕见的肌纤维瘤病例，该病例在一名 2 岁男孩中表现为牙源性病变的类似物。该患者因右侧下颌支无痛性肿胀而偶然发现，其病因不明。影像学分析显示，右侧下颌第一磨牙生发区附近有一个实性、膨胀性病变。经切开活检的组织病理学分析和免疫组织化学检查提示可能为中央性牙源性纤维瘤，患者接受了全切除术，最终诊断为颌骨内肌纤维瘤。随访检查未发现复发迹象。
本报告有助于了解儿科患者的肌纤维瘤，并强调了细致的组织病理学检查对于有效手术计划和最佳患者结局的关键作用。
