Aryanpour Zain, Maglic Dino, Zahid Rehan, Tuncer Fatma B, Gociman Barbu R, Siddiqi Faizi A
School of Medicine, University of Alabama at Birmingham, Birmingham, Ala.
Department of Surgery, Division of Plastic Surgery, University of Utah, Salt Lake City, Utah.
Plast Reconstr Surg Glob Open. 2022 Jun 14;10(6):e4380. doi: 10.1097/GOX.0000000000004380. eCollection 2022 Jun.
A female child was investigated for insidious onset of temporomandibular joint dysfunction and trismus in the setting of a mandibular myofibroma. Myofibromas, benign mesenchymal neoplasms composed of spindle cells, are rarely found in the oral cavity, most commonly in the mandible. These lesions are historically described as indolent with a high cure rate and minimal recurrence rates following surgical resection. The patient initially presented with concerns regarding snoring, retrognathia, and jaw ankylosis, as well as a history of trouble latching as an infant but without obvious physical deformities. Imaging revealed a large expansile lytic mass of the mandible, but no temporomandibular joint involvement; surgical biopsy evidenced myofibroma, and the lesion was resected. Over the course of disease, the lesion continued to expand, and the patient's maximal incisal opening continued to decrease despite conservative management with jaw physiotherapy; eventually she could not open her mouth despite the absence of joint involvement. Re-exploration along with formal jaw physiotherapy was achieved and optimal jaw opening was maintained. Myofibromas are rare benign desmoid tumors that can present anywhere in the body in solitary and multicentric forms, and previously did not present significant challenges to surgical and medical management. Tumors of the mandible may present with trismus and soft tissue ankylosis, which can mimic temporomandibular joint dysfunction in the absence of joint involvement. Physical therapy, rehabilitation, and soft tissue contracture release are key to management and improving outcomes in oral cancer patients, regardless of tumor pathology.
一名女童因下颌骨肌纤维瘤出现颞下颌关节功能障碍和牙关紧闭的隐匿性发作而接受检查。肌纤维瘤是由梭形细胞组成的良性间叶性肿瘤,在口腔中很少见,最常见于下颌骨。从历史上看,这些病变被描述为生长缓慢,手术切除后治愈率高且复发率低。患者最初表现出打鼾、下颌后缩和颌关节强直等问题,以及婴儿期吸吮困难的病史,但无明显身体畸形。影像学检查显示下颌骨有一个巨大的膨胀性溶骨性肿块,但未累及颞下颌关节;手术活检证实为肌纤维瘤,病变被切除。在疾病过程中,病变持续扩大,尽管进行了颌部物理治疗等保守治疗,患者的最大切牙开口度仍持续减小;最终,尽管未累及关节,她仍无法张口。再次进行手术并配合正规的颌部物理治疗,使患者维持了最佳的张口度。肌纤维瘤是罕见的良性硬纤维瘤,可单发或多发于身体任何部位,以前在手术和药物治疗方面并未带来重大挑战。下颌骨肿瘤可能表现为牙关紧闭和软组织强直,在未累及关节的情况下可模拟颞下颌关节功能障碍。物理治疗、康复治疗和软组织挛缩松解是口腔癌患者管理和改善预后的关键,无论肿瘤病理类型如何。