Suppr超能文献

一名15岁患者下颌骨骨内肌纤维瘤:病例报告及文献复习

Intraosseous myofibroma of the mandible in a 15 year old: case report and review of the literature.

作者信息

Loh Charlotte, Alshammasi Raghad, Crotty Thomas J, Fatima Arooj, O'Neill John, Murray Dylan J, Heffernan Colleen B

机构信息

Department of Otolaryngology-Head & Neck Surgery, Children's Health Ireland at Temple Street, Dublin D0XD99, Ireland.

Department of Surgery, Royal College of Surgeons Ireland, Dublin D02YN77, Ireland.

出版信息

J Surg Case Rep. 2025 Aug 13;2025(8):rjaf563. doi: 10.1093/jscr/rjaf563. eCollection 2025 Aug.

Abstract

Myofibromas are rare, benign spindle cell tumours occuring in the first two decades of life, with predilection for the head and neck region. Intraosseous myofibromas of the mandible are exceptionally rare, with fewer than 50 reported cases. We describe the case of a 15-year-old male with an enlarging, painless oral mass causing third molar displacement. Examination revealed an exophytic sublingual lesion with a necrotic surface. Imaging demonstrated a well-defined osteolytic lesion in the mandibular body with soft tissue extension. Biopsy confirmed intraosseous myofibroma, characterized by bland spindle cell proliferation and hemangiopericytoma-like vasculature. The patient underwent a marginal mandibulectomy. Postoperative recovery was uneventful; follow-up imaging at 6 months confirmed no recurrence. Oral rehabilitation is ongoing. This case highlights the importance of accurate diagnosis and multidisciplinary management in treating rare mandibular tumours. Surgical resection remains the definitive treatment.

摘要

肌纤维瘤是罕见的良性梭形细胞瘤,发生于生命的前二十年,好发于头颈部区域。下颌骨骨内肌纤维瘤极为罕见,报告病例少于50例。我们描述了一名15岁男性患者的病例,其口腔肿物不断增大且无痛,导致第三磨牙移位。检查发现一个有坏死表面的外生性舌下病变。影像学检查显示下颌骨体部有一个边界清晰的溶骨性病变并伴有软组织延伸。活检证实为骨内肌纤维瘤,其特征为温和的梭形细胞增殖和类似血管外皮细胞瘤的脉管系统。患者接受了下颌骨边缘切除术。术后恢复顺利;6个月的随访影像学检查证实无复发。口腔修复正在进行中。该病例强调了准确诊断和多学科管理在治疗罕见下颌骨肿瘤中的重要性。手术切除仍然是 definitive治疗方法。 (注:原文中“definitive”此处直接保留英文未翻译准确,可译为“决定性的”等合适表述)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6705/12346434/5bac65cf75cd/rjaf563f1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验