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运动和体育干预对创伤后应激障碍风险的被迫流离失所者认知功能和疼痛的影响:SALEEM 随机对照试验的二次分析。

The impact of an exercise and sport intervention on cognitive function and pain among forcibly displaced individuals at risk for PTSD: a secondary analysis of the SALEEM randomized controlled trial.

机构信息

Department of Sport, Exercise and Health, University of Basel, Grosse Alle 6, 4052, Basel, Switzerland.

Department of Physical Education and Sport Sciences, University of Thessaly, 42100, Trikala, Greece.

出版信息

BMC Med. 2024 Sep 12;22(1):387. doi: 10.1186/s12916-024-03601-x.

Abstract

BACKGROUND

In response to the global scope of forced displacement, international organizations highlight the need of scalable solutions to support individuals' health and integration into host societies. Exposure to high mental and physical stress perceived before, during, and after displacement can impair functional capabilities, essential for adapting to a new environment. This secondary analysis examined the impact of an exercise and sport intervention on cognitive function and pain severity among individuals living in a refugee camp in Greece.

METHODS

We implemented a randomized controlled trial involving n = 142 (52.8% women) forcibly displaced individuals from Southwest Asia and Sub-Saharan Africa. Participants were randomly assigned to a waitlist or a 10-week co-designed exercise and sport intervention with a 1:1 allocation rate between groups and sexes. Assessments at baseline and follow-up included the Flanker task, the Oddball paradigm, pain severity via visual analog scales, and the Åstrand-Rhyming indirect test of maximal oxygen uptake. We analyzed the intervention effects using structural equation modeling.

RESULTS

Our findings did not indicate a direct intervention effect on cognitive function or pain (p ≥ .332). However, the intervention group significantly improved cardiorespiratory fitness, ß = .17, p = .010, which was associated with faster reaction times in cognitive tasks, ß =  - .22, p = .004. Moreover, there was some evidence that adherence might be linked to reduced pain severity, ß =  - .14, p = .065.

CONCLUSIONS

Exercise and sport did not directly impact cognitive function and pain severity among a sociodemographically diverse sample living in a refugee camp, suggesting the need for complementary measures. Nevertheless, our results indicate that improvements in cardiorespiratory fitness benefit aspects of attention.

TRIAL REGISTRATION

The study was approved by the local ethics committee of the University of Thessaly (no. 39) and registered prospectively on February 8, 2021 at the ISRCTN registry (no. 16291983).

摘要

背景

面对全球范围的被迫流离失所现象,国际组织强调需要可扩展的解决方案来支持个人的健康和融入收容社会。在流离失所之前、期间和之后,人们会经历高强度的身心压力,这可能会损害他们适应新环境所需的基本功能能力。本二次分析研究了在希腊难民营中,一项锻炼和运动干预对个体认知功能和疼痛严重程度的影响。

方法

我们实施了一项随机对照试验,涉及来自西南亚和撒哈拉以南非洲的 142 名(52.8%为女性)被迫流离失所的个体。参与者被随机分配到等待名单或为期 10 周的共同设计的锻炼和运动干预组,组间和性别间的分配比例为 1:1。基线和随访时的评估包括 Flanker 任务、Oddball 范式、视觉模拟量表评估的疼痛严重程度以及 Åstrand-Rhyming 间接测试最大摄氧量。我们使用结构方程模型分析了干预效果。

结果

我们的研究结果并未表明认知功能或疼痛有直接的干预效果(p≥.332)。然而,干预组的心肺功能适应性显著提高,β=0.17,p=0.010,这与认知任务中的反应时间加快有关,β=−0.22,p=0.004。此外,有一些证据表明,坚持锻炼可能与疼痛严重程度降低有关,β=−0.14,p=0.065。

结论

对于居住在难民营中的社会人口统计学上多样化的样本,锻炼和运动并没有直接影响认知功能和疼痛严重程度,这表明需要采取补充措施。然而,我们的研究结果表明,心肺功能适应性的提高有益于注意力的各个方面。

试验注册

该研究得到了塞萨利大学当地伦理委员会(编号 39)的批准,并于 2021 年 2 月 8 日在 ISRCTN 注册处(编号 16291983)进行了前瞻性注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4acb/11396323/86251da2784d/12916_2024_3601_Fig1_HTML.jpg

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