Wang Zhen, Liang Ming, Sun Jingyang, Zhang Jie, Li Yunhao, Xu Lisheng, Han Yaling
College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, China.
Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Front Cardiovasc Med. 2024 Aug 29;11:1445424. doi: 10.3389/fcvm.2024.1445424. eCollection 2024.
Pulsed-field ablation (PFA) technique is a nonthermal ablation technique. No study has yet evaluated the effect of the positional relationship between the ablation electrode (AE) and the coronary metal stent (CMS) on the electric field distribution and temperature distribution in epicardial ablation. Our study aimed to evaluate the effect of the CMS on the electric field as well as the temperature distribution in different models.
Multi-angle modeling of the CMS and AE was performed. The PFA ablation region was evaluated with a field strength contour of 1,000 V/cm, which was used to assess the validity of the two-dimensional (2D) model simulation data as well as the distribution of the multi-angle electric field and temperature in the three-dimensional (3D) model.
The presence of the CMS had little effect on the width of the ablation area (0.2 mm). In the 3D model, the temperature of the ablation area was highest when the angle between the AE and the CMS was in the 90° position (43.4°C, 41.3°C); a change in the distance between the AE and the CMS affected the temperature of the ablation area (maximum 2.1°C) and the width of the ablation (maximum 0.32 mm).
The presence of the CMS distorts the distribution of the electric field, but does not produce a change in the extent of the ablation damage, nor does it bring thermal damage to the ablation region. Different simulation models give similar results in PFA calculations, and this study effectively reduces the complexity of modeling simulation.
脉冲场消融（PFA）技术是一种非热消融技术。尚无研究评估消融电极（AE）与冠状动脉金属支架（CMS）之间的位置关系对心外膜消融中电场分布和温度分布的影响。我们的研究旨在评估CMS在不同模型中对电场以及温度分布的影响。
对CMS和AE进行多角度建模。使用1000 V/cm的场强等高线评估PFA消融区域，用于评估二维（2D）模型模拟数据的有效性以及三维（3D）模型中多角度电场和温度的分布。
CMS的存在对消融区域宽度（0.2 mm）影响不大。在3D模型中，当AE与CMS之间的角度处于90°位置时，消融区域温度最高（43.4°C，41.3°C）；AE与CMS之间距离的变化影响消融区域温度（最大2.1°C）和消融宽度（最大0.32 mm）。
CMS的存在会使电场分布发生畸变，但不会使消融损伤范围发生变化，也不会给消融区域带来热损伤。不同的模拟模型在PFA计算中给出了相似的结果，本研究有效降低了建模模拟的复杂性。
