Adhikari Bipin, Adhikari Biplab, Madichetty Hari G, Dhital Alina, Kanugula Ashok Kumar
Internal Medicine, Wellstar Spalding Medical Center, Griffin, USA.
Infectious Diseases, University of Louisville School of Medicine, Louisville, USA.
Cureus. 2024 Aug 12;16(8):e66690. doi: 10.7759/cureus.66690. eCollection 2024 Aug.
Yellow nail syndrome is a rare medical syndrome characterized by the combination of a triad of yellow nails, recurrent pulmonary manifestations, and lymphedema. All three features of the triad may not be present synchronously. The diagnosis is made clinically once other causes have been excluded. Typically, it occurs in individuals who are 50 years old and above. We report a case of yellow nail syndrome in a 62-year-old male who presented with recurrent episodes of difficulty breathing due to pleural effusion. Further examination revealed pitting edema of the bilateral lower extremities. In the later encounter, his nail was found to be yellowish. Excluding other diagnoses like heart failure, fungal infections, autoimmune diseases, and lung cancer, with a typical triad, a diagnosis of yellow nail syndrome was made. He was managed with pleural fluid tapping for pleural effusion, compression stockings for leg edema, and vitamin E for nail changes. The study also intends to highlight current treatment options and alert physicians of this syndrome with such typical findings.
黄甲综合征是一种罕见的医学综合征，其特征为黄甲、反复出现的肺部表现和淋巴水肿三联征。三联征的所有三个特征可能不会同时出现。一旦排除其他病因，即可临床诊断。通常，它发生在50岁及以上的人群中。我们报告一例62岁男性黄甲综合征病例，该患者因胸腔积液反复出现呼吸困难。进一步检查发现双侧下肢凹陷性水肿。在后来的会诊中，发现他的指甲发黄。排除心力衰竭、真菌感染、自身免疫性疾病和肺癌等其他诊断，结合典型的三联征，诊断为黄甲综合征。对其胸腔积液进行胸腔穿刺抽液治疗，腿部水肿使用弹力袜，指甲改变使用维生素E治疗。该研究还旨在强调当前的治疗选择，并提醒医生注意具有此类典型表现的该综合征。
