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基于高胆固醇血症诊断毛发石:一例报告

The Diagnosis of Trichobezoar Based on the Presence of Hypercholesterolemia: A Case Report.

作者信息

Tsuchiya Toui, Nii Kohichiroh, Yamamoto Mayumi, Tanaka Aya, Kusaka Takashi

机构信息

Department of Pediatrics, Shodoshima Central Hospital, Kagawa, JPN.

Pediatric Surgery, Kagawa University, Kagawa, JPN.

出版信息

Cureus. 2024 Aug 13;16(8):e66758. doi: 10.7759/cureus.66758. eCollection 2024 Aug.

DOI:10.7759/cureus.66758
PMID:39268303
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11391662/
Abstract

Trichobezoar refers to the collection of ingested hair accumulating in the gastric mucosa folds, which are found in patients with trichotillomania and trichophagia. We present a case of a nine-year-old girl in Japan who was found to have hypercholesterolemia in the universal lipid screening as a part of the annual health checkups for the prevention of lifestyle-related diseases. Further examination revealed a palpable mass without any digestive symptoms. Imaging studies and the patient's history of pica indicated trichobezoar and upper gastrointestinal endoscopy revealed a large hairball occupying the entire lumen of the stomach. Thereafter, the large trichobezoar was removed by laparotomy and psychological support was provided to her to prevent its recurrence. Hypercholesterolemia improved after the removal of trichobezoar, which suggests an association between a large trichobezoar and cholesterol metabolism. Hypercholesterolemia may serve as a clue to the identification of trichobezoar.

摘要

毛石是指摄入的毛发聚集在胃黏膜皱襞中,见于拔毛癖和食毛癖患者。我们报告一例日本9岁女孩的病例,在作为预防生活方式相关疾病年度健康检查一部分的通用血脂筛查中发现她患有高胆固醇血症。进一步检查发现一个可触及的肿块,且无任何消化症状。影像学检查和该患者的异食癖病史提示为毛石,上消化道内镜检查发现一个巨大毛球占据了整个胃腔。此后,通过剖腹手术取出了巨大毛石,并为她提供了心理支持以防止复发。取出毛石后高胆固醇血症有所改善,这表明巨大毛石与胆固醇代谢之间存在关联。高胆固醇血症可能是识别毛石的一个线索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1644/11391662/09602cd2f8af/cureus-0016-00000066758-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1644/11391662/09602cd2f8af/cureus-0016-00000066758-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1644/11391662/09602cd2f8af/cureus-0016-00000066758-i01.jpg

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本文引用的文献

1
Universal Screening for Familial Hypercholesterolemia in Children in Kagawa, Japan.日本香川县对儿童家族性高胆固醇血症的普筛
J Atheroscler Thromb. 2022 Jun 1;29(6):839-849. doi: 10.5551/jat.62780. Epub 2021 Jun 26.
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Medical and behavioral evaluation of 8 cats presenting with fabric ingestion: An exploratory pilot study.8只出现吞食织物情况的猫的医学和行为评估:一项探索性初步研究。
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A rare clinic entity: Huge trichobezoar.一种罕见的临床实体:巨大毛石。
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Trichobezoar, rapunzel syndrome, tricho-plaster bezoar - a report of three cases.毛发石、长发公主综合征、毛发石膏石——三例报告
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Clinical characteristics of trichotillomania with trichophagia.拔毛癖伴食毛症的临床特征
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Etiology of hypercholesterolemia in patients with anorexia nervosa.神经性厌食症患者高胆固醇血症的病因
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