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Combining immunotherapy with PARP inhibitors. Is it possible to find the way through?

作者信息

Papageorgiou Georgios I, Skouteris Nikolaos, Eleftheriou Kleopatra, Kosmas Christos

机构信息

2nd Medical Oncology Department, IASO General Clinic, Athens, Greece.

Division of Medical Oncology & Hematopoietic Cell Transplant Unit, Department of Medicine, "Metaxa" Cancer Hospital, Piraeus, Greece.

出版信息

Immunotherapy. 2024;16(16-17):999-1003. doi: 10.1080/1750743X.2024.2398412. Epub 2024 Sep 13.

DOI:10.1080/1750743X.2024.2398412
PMID:39268937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11492662/
Abstract
摘要

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本文引用的文献

1
PARP Inhibitors: Strategic Use and Optimal Management in Ovarian Cancer.PARP抑制剂：卵巢癌的策略性应用与优化管理
Cancers (Basel). 2024 Feb 25;16(5):932. doi: 10.3390/cancers16050932.
2
First-line talazoparib with enzalutamide in HRR-deficient metastatic castration-resistant prostate cancer: the phase 3 TALAPRO-2 trial.一线 talazoparib 联合恩扎卢胺治疗 HRR 缺陷转移性去势抵抗性前列腺癌：III 期 TALAPRO-2 试验。
Nat Med. 2024 Jan;30(1):257-264. doi: 10.1038/s41591-023-02704-x. Epub 2023 Dec 4.
3
Olaparib plus Durvalumab, with or without Bevacizumab, as Treatment in PARP Inhibitor-Naïve Platinum-Sensitive Relapsed Ovarian Cancer: A Phase II Multi-Cohort Study.奥拉帕利联合度伐利尤单抗，联合或不联合贝伐珠单抗，用于 PARP 抑制剂初治铂类敏感复发性卵巢癌的治疗：一项 II 期多队列研究。
Clin Cancer Res. 2024 Jan 5;30(1):50-62. doi: 10.1158/1078-0432.CCR-23-2249.
4
Durvalumab Plus Carboplatin/Paclitaxel Followed by Maintenance Durvalumab With or Without Olaparib as First-Line Treatment for Advanced Endometrial Cancer: The Phase III DUO-E Trial.度伐利尤单抗联合卡铂/紫杉醇序贯度伐利尤单抗维持治疗（联合或不联合奥拉帕利）作为晚期子宫内膜癌一线治疗：III期DUO-E试验
J Clin Oncol. 2024 Jan 20;42(3):283-299. doi: 10.1200/JCO.23.02132. Epub 2023 Oct 21.
5
Current Understanding on Why Ovarian Cancer Is Resistant to Immune Checkpoint Inhibitors.当前对卵巢癌为何对免疫检查点抑制剂产生耐药性的认识。
Int J Mol Sci. 2023 Jun 29;24(13):10859. doi: 10.3390/ijms241310859.
6
Crosstalk between immune checkpoint and DNA damage response inhibitors for radiosensitization of tumors.免疫检查点与 DNA 损伤反应抑制剂的串扰增强肿瘤放疗增敏作用。
Strahlenther Onkol. 2023 Dec;199(12):1152-1163. doi: 10.1007/s00066-023-02103-8. Epub 2023 Jul 7.
7
Early-Stage Triple-Negative Breast Cancer Journey: Beginning, End, and Everything in Between.早期三阴性乳腺癌之旅：起点、终点及其间的一切。
Am Soc Clin Oncol Educ Book. 2023 Jun;43:e390464. doi: 10.1200/EDBK_390464.
8
Olaparib plus bevacizumab first-line maintenance in ovarian cancer: final overall survival results from the PAOLA-1/ENGOT-ov25 trial.奥拉帕利联合贝伐珠单抗一线维持治疗卵巢癌：PAOLA-1/ENGOT-ov25 试验的最终总生存结果。
Ann Oncol. 2023 Aug;34(8):681-692. doi: 10.1016/j.annonc.2023.05.005. Epub 2023 May 19.
9
Adjuvant Olaparib for Germline BRCA Carriers With HER2-Negative Early Breast Cancer: Evidence and Controversies.辅助奥拉帕利治疗 HER2 阴性早期乳腺癌的胚系 BRCA 携带者：证据与争议。
Oncologist. 2023 Jul 5;28(7):565-574. doi: 10.1093/oncolo/oyad123.
10
Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer.帕博利珠单抗联合化疗治疗晚期子宫内膜癌。
N Engl J Med. 2023 Jun 8;388(23):2159-2170. doi: 10.1056/NEJMoa2302312. Epub 2023 Mar 27.