Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Curr Opin Support Palliat Care. 2024 Dec 1;18(4):260-268. doi: 10.1097/SPC.0000000000000725. Epub 2024 Oct 30.
Two commonly used quality of life (QoL) questionnaires in lung cancer patients are the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Lung Cancer 13 (QLQ-LC13) and the Functional Assessment of Cancer Therapy-Lung (FACT-L). More recently, the EORTC QLQ-LC29 was developed. This systematic review compares the EORTC QLQ-LC29, EORTC QLQ-LC13 and FACT-L in terms of the content, validity and psychometric properties in assessing the QoL of lung cancer patients.
Fourteen studies were included. The EORTC QLQ-LC29 is a 29-item scale that serves as an update of the EORTC QLQ-LC13 to include symptoms from surgery and new targeted therapies. It shows validity, high internal consistency, test-retest reliability, and sensitivity. The FACT-L continues to assess general quality of life and lung cancer-specific symptoms.
The EORTC QLQ-LC29, EORTC QLQ-LC13, and FACT-L were reviewed to assess their validity in measuring QoL of lung cancer patients. All were found to be sufficiently validated, The choice of which to use should depend on the primary goals of the study.
两种常用于肺癌患者的生活质量（QoL）问卷是欧洲癌症研究与治疗组织（EORTC）肺癌 13 项生活质量问卷（QLQ-LC13）和癌症治疗功能评估-肺（FACT-L）。最近，EORTC QLQ-LC29 也被开发出来。本系统综述比较了 EORTC QLQ-LC29、EORTC QLQ-LC13 和 FACT-L 在评估肺癌患者生活质量方面的内容、有效性和心理测量特性。
纳入了 14 项研究。EORTC QLQ-LC29 是一个 29 项的量表，它是 EORTC QLQ-LC13 的更新版本，包括了手术和新的靶向治疗的症状。它具有有效性、高内部一致性、重测信度和敏感性。FACT-L 继续评估一般生活质量和肺癌特异性症状。
综述了 EORTC QLQ-LC29、EORTC QLQ-LC13 和 FACT-L，以评估它们在测量肺癌患者生活质量方面的有效性。所有这些都被认为是足够有效的。选择使用哪种问卷应取决于研究的主要目标。
