Altern Ther Health Med. 2024 Sep;30(9):36-41.
Allergic rhinitis (AR) is a common immune disease of the nasal mucosa, and anti-allergenic medications provide only momentary relief. Multiple factors, such as rising pollution, especially in urban areas; dust particles, such as from air conditioners; house mites; and the use of chemicals and aromatic products can stimulate AR.
The literature review intended to examine the effectiveness of homoeopathic remedies in immune- and inflammatory-model systems based on the basic homoeopathic principle-the law of similarity of pharmacological action at the cellular level-and to evaluate the effects of dilution or dynamization on the drug activity of Wyethia tested under controlled settings, interpreting data based on similarity.
The research team performeda narrative review by searching Google scholar & Pubmed databases. The search usedthe keywords "Wyethia Helenioides", "Allergic Rhinitis", "Homoeopathy", "Homeopathy", "Anti-inflammatory", "Invitro", "Invivo", "Clinical Trial", "Case report" & "Flavanoids".
The study took place at Department of Homoeopathic Materia Medica, Dr. D Y Patil Homoeopathic Medical College and Research Institute, Pimpri, Pune, Maharashtra, India.
Clinical observations indicated that the homoeopathic preparations of Wyethia in low concentrations, even beyond Avogadro's number, may have antimicrobial, antioxidant, and anti-inflammatory properties. The hormesis concept-a biphasic dose response with a low-dose stimulation or beneficial effect and a high dose inhibitory or toxic effect-may explain the effects against human mast cells(HMC-1s).
Clinical observations indicate that the homoeopathic preparations of Wyethia in low concentrations, even beyond Avogadro's number, might show anti-inflammatory properties that the hormesis concept against HMC-1 can explain. The current research team thus anticipates that the analysis of this little-known material will provide a novel and insightful look at the state-of-the-art of homoeopathy without drawing any firm judgments for or against this treatment. Although it could be challenging to accept, it's currently the most receptive stance.
过敏性鼻炎（AR）是一种常见的鼻黏膜免疫疾病，抗过敏原药物只能提供暂时的缓解。多种因素，如不断上升的污染，特别是在城市地区；空调等灰尘颗粒；屋尘螨；以及化学物质和芳香产品的使用，都会刺激 AR。
文献综述旨在根据基本顺势疗法原则——细胞水平的药理学作用相似性法则，检查顺势疗法药物在免疫和炎症模型系统中的疗效，并评估在受控条件下测试 Wyethia 的稀释或动态作用对药物活性的影响，根据相似性解释数据。
研究团队通过搜索 Google Scholar 和 PubMed 数据库进行了叙述性综述。该搜索使用了关键词“Wyethia Helenioides”、“过敏性鼻炎”、“顺势疗法”、“顺势疗法”、“抗炎”、“体外”、“体内”、“临床试验”、“病例报告”和“类黄酮”。
该研究在印度马哈拉施特拉邦浦那市 Dr. D Y Patil 顺势疗法医学学院和研究所的顺势疗法药物学系进行。
临床观察表明，Wyethia 的顺势疗法制剂即使在阿伏伽德罗数之外的低浓度下，也可能具有抗菌、抗氧化和抗炎特性。 hormesis 概念——一种具有低剂量刺激或有益作用和高剂量抑制或毒性作用的双相剂量反应——可能解释其对人肥大细胞（HMC-1s）的作用。
临床观察表明，Wyethia 的顺势疗法制剂即使在阿伏伽德罗数之外的低浓度下，也可能具有抗炎特性，hormesis 概念可以解释对 HMC-1 的作用。因此，当前的研究团队预计，对这种鲜为人知的物质的分析将为顺势疗法的最新技术提供一个新颖而有见地的视角，而不会对这种治疗方法做出任何肯定或否定的判断。尽管这可能难以接受，但这是目前最具接受性的立场。
