封锁 SIRT4。
Lock out SIRT4.
机构信息
School of Biomedical Sciences, University of Hong Kong, Hong Kong, Hong Kong.
出版信息
Elife. 2024 Sep 13;13:e102355. doi: 10.7554/eLife.102355.
Abstract
The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
摘要
SIRT4 在肾细胞核中的积累会导致肾纤维化，因此阻止这种蛋白质的运动可能是对抗纤维化的一种潜在治疗策略。
Zotero 插件