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马拉维高血压护理偏好:针对患有和未患有艾滋病毒的高血压患者的离散选择实验

Preferences for Hypertension Care in Malawi: A Discrete Choice Experiment Among People Living with Hypertension, With and Without HIV.

作者信息

Hoffman Risa, Phiri Khumbo, Kalande Pericles, Whitehead Hannah, Moses Agnes, Rockers Peter C, Tseng Chi-Hong, Talama George, Banda Jonathan Chiwanda, van Oosterhout Joep J, Phiri Sam, Moucheraud Corrina

机构信息

David Geffen School of Medicine, Department of Medicine, Division of Infectious Diseases, University of California, Risa Hoffman, 911 Broxton Avenue Suite 301D, Los Angeles, CA, 90024, USA.

Partners in Hope Medical Center, Lilongwe, Malawi.

出版信息

AIDS Behav. 2025 Jan;29(1):246-256. doi: 10.1007/s10461-024-04492-y. Epub 2024 Sep 13.

Abstract

Hypertension is the most common non-communicable disease diagnosed among people in sub-Saharan Africa. However, little is known about client preferences for hypertension care. We performed a discrete choice experiment in Malawi among people with hypertension, with and without HIV. Participants were asked to select between two care scenarios, each with six attributes: distance, waiting time, provider friendliness, individual or group care, antihypertensive medication supply, and antihypertensive medication dispensing frequency (three versus one month). Eight choice sets (each with two scenarios) were presented to each individual. Mixed effects logit models quantified preferences for each attribute. Estimated model coefficients were used to predict uptake of hypothetical models of care. Between July 2021 and April 2022 we enrolled 1003 adults from 14 facilities in Malawi; half were living with HIV and on ART for a median of 11 years. Median age of respondents was 57 years (IQR 49-63), 58.2% were female, and median duration on antihypertensive medications was 4 years (IQR 2-7). Participants strongly preferred seeing a provider alone versus in a group (OR 11.3, 95% CI 10.4-12.3), with stronger preference for individual care among those with HIV (OR 15.4 versus 8.6, p < 0.001). Three-month versus monthly dispensing was also strongly preferred (OR 4.2; 95% CI 3.9-4.5). 72% of respondents would choose group care if all other facility attributes were favorable, although PLHIV were less likely to make this trade-off (66% versus 77%). These findings have implications for the scale-up of hypertension care in Malawi and similar settings.

摘要

高血压是撒哈拉以南非洲地区人群中最常见的非传染性疾病。然而,对于高血压护理的患者偏好却知之甚少。我们在马拉维对患有和未患有艾滋病毒的高血压患者进行了一项离散选择实验。参与者被要求在两种护理场景之间进行选择,每个场景有六个属性:距离、等待时间、医护人员友好程度、个体或团体护理、抗高血压药物供应以及抗高血压药物配药频率(三个月一次与一个月一次)。向每个人展示了八个选择集(每个选择集包含两种场景)。混合效应逻辑模型量化了对每个属性的偏好。估计的模型系数用于预测假设护理模式的接受情况。在2021年7月至2022年4月期间,我们从马拉维的14个医疗机构招募了1003名成年人;其中一半感染了艾滋病毒并接受抗逆转录病毒治疗,治疗时间中位数为11年。受访者的年龄中位数为57岁(四分位间距49 - 63岁),58.2%为女性,服用抗高血压药物的时间中位数为4年(四分位间距2 - 7年)。参与者强烈倾向于单独看医护人员而非团体就诊(优势比11.3,95%置信区间10.4 - 12.3),艾滋病毒感染者对个体护理的偏好更强(优势比15.4对8.6,p < 0.001)。与每月配药相比,三个月配药也更受青睐(优势比4.2;95%置信区间3.9 - 4.5)。如果所有其他医疗机构属性都有利,72%的受访者会选择团体护理,尽管艾滋病毒感染者做出这种权衡的可能性较小(66%对77%)。这些发现对马拉维和类似环境中高血压护理的扩大规模具有启示意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b46b/11739184/62ece550f0f8/10461_2024_4492_Fig1_HTML.jpg

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