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非洲国家基本药物的可及性和可负担性面临的挑战:一项范围综述

Challenges to the Availability and Affordability of Essential Medicines in African Countries: A Scoping Review.

作者信息

Yenet Aderaw, Nibret Getinet, Tegegne Bantayehu Addis

机构信息

Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

出版信息

Clinicoecon Outcomes Res. 2023 Jun 13;15:443-458. doi: 10.2147/CEOR.S413546. eCollection 2023.

Abstract

INTRODUCTION

The availability and affordability of safe, effective, accessible, and high-quality essential medicines is a critical benchmark for achieving the right to good health, and it is also one of the goals of the global health development agenda. To that end, it is critical to conduct rigorous studies to identify the major challenges confronting developing countries, particularly those in Africa.

OBJECTIVE

The purpose of this review was to identify the major challenges that Africans face in obtaining reasonably priced and readily available essential medicines.

METHODS

Generally the Boolean operators "AND" and "OR" were employed. Making progress also involves using duplicate checks, field definitions, and comparisons of articles and criteria. The analysis included all English-language papers published in any African country between 2005 and 2022, depending on the year of publication. The technique searches electronic databases for key phrases related to essential medication availability and affordability, such as PubMed, Web of Science, Scopus, Science Direct, Plos Medicine, and Google Scholar.

RESULTS

A total of 91 articles; by using search engines and handpicking including duplicates, were primarily searched. The electronic database search earned 78 articles while only eleven studies met the criteria for review and were reviewed of which 5 (50%) were from East African countries. Inadequate human resources, financial constraints, high cost of available medications on the market, poor inventory management, manual consumption forecasting, inefficiencies in drug registration, and trade-related aspects of intellectual property rights agreement regulations are all obstacles to the availability of essential medicines in African nations.

CONCLUSION

This review revealed that in Africa, the availability and affordability of essential medicines face numerous challenges. The primary challenge, according to the review research, is a lack of adequate financing to pay for an appropriate set of essential medications, which account for a significant portion of household spending.

摘要

引言

安全、有效、可及且高质量的基本药物的可获得性和可负担性是实现健康权的关键基准,也是全球卫生发展议程的目标之一。为此,开展严谨研究以确定发展中国家,尤其是非洲国家所面临的主要挑战至关重要。

目的

本综述的目的是确定非洲人在获取价格合理且易于获得的基本药物方面面临的主要挑战。

方法

一般采用布尔运算符“AND”和“OR”。取得进展还涉及使用重复检查、字段定义以及文章和标准的比较。根据出版年份,分析包括2005年至2022年期间在任何非洲国家发表的所有英文论文。该技术在电子数据库中搜索与基本药物可获得性和可负担性相关的关键词组,如PubMed、科学网、Scopus、科学Direct、公共科学图书馆·医学和谷歌学术。

结果

共检索到91篇文章;通过使用搜索引擎和人工挑选(包括重复文章)进行初步检索。电子数据库搜索获得78篇文章,而只有11项研究符合综述标准并进行了综述,其中5项(50%)来自东非国家。人力资源不足、资金限制、市场上现有药物成本高昂、库存管理不善、人工消费预测、药品注册效率低下以及与贸易相关的知识产权协议法规等都是非洲国家基本药物可获得性的障碍。

结论

本综述表明,在非洲,基本药物的可获得性和可负担性面临诸多挑战。根据综述研究,主要挑战是缺乏足够资金来支付一套合适的基本药物,而这些药物在家庭支出中占很大一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7d/10276598/3cbeab2d22b4/CEOR-15-443-g0001.jpg

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